EC Number   |
Activating Compound |
Reference |
|---|
   3.6.5.4 | 4.5S RNA |
accelerates the association between Ffh and FtsY 400fold in their GTP-bound form and thereby stimulates GTPase activity |
657913 |
| 3.6.5.4 | 4.5S RNA |
stimulates GTPase activity in the SRP-FtsY complex in vitro and is essential for SRP function in vivo |
690025 |
| 3.6.5.4 | cpFtsY |
chlorplastic cell division protein FtsY homologue, a signal recognition particle receptor protein, also shows GTPase activity |
757189 |
| 3.6.5.4 | FtsY |
GTPase subunit of the bacterial SRP receptor activates Ffh, reciprocal GTPase activation mechanism |
660353 |
| 3.6.5.4 | FtsY |
GTPase subunit of the bacterial SRP receptor, both Ffh and FtsY act as GTPase activating proteins for one another, resulting in a mutual stimulation of GTP hydrolysis by both proteins |
657913 |
| 3.6.5.4 | FtsY |
GTPase subunit of the SRP receptor activates Ffh, Ffh and FtsY reciprocally regulate each others GTPase activity |
658538 |
| 3.6.5.4 | GTP |
GTP binding to both the SRP and SR is a prerequisite for the formation of the SRP-SR complex in which GTP hydrolysis is activated in a composite active site |
686249 |
| 3.6.5.4 | more |
the FtsY GTPase is activated by formation of the targeting complex as well as upon membrane interaction, but homodimerization of FtsY also stimulates its GTPase activity |
758489 |
| 3.6.5.4 | signal recognition particle receptor |
SRP and its receptor stimulate each others GTPase activity, mechanism of reciprocal activation, substrate twinning activates the signal recognition particle and its receptor |
660000 |
| 3.6.5.4 | signal recognition particle RNA |
SRP RNA, the signal recognition particle RNA distal end triggers GTP hydrolysis in the signal recognition particle protein-SRP receptor GTPase, i.e. Ffh-FtsY GTPase, complex. An intact docking site at the distal end of SRP RNA is required to stimulate GTPase activation. Loop E plays a crucial role in GTPase activation by the SRP RNA |
734245 |
