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Results 1 - 10 of 14 > >>
EC Number Activating Compound Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6Ist1 addition of the endosomal sorting complex required for the transport III (ESCRT-III) subunit binding partner of Ist1, Did2, converts ESCRT-III subunit Ist1 from an inhibitor to a stimulator of the enzyme (maximal stimulation at 0.008 or less mM). Mutants Ist1(L168A/Y172A) and Ist1(K135A) hyperstimulate enzyme ATPase activity 757152
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6LIP5 - 689461
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6LIP5F388A a weak SKD1 interactor, complements the lip5 mutant for heat and salt stress tolerance, most likely due to its overexpression driven by the strong CaMV 35S promoter in the transgenic plants 734975
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6Lyst-interacting protein5 LIP5, interacts strongly with enzyme SKD1 and stimulates the ATPase activity of the enzyme by 4 to 5fold. LIP5 is a positive regulator of enzyme SKD1 in multivesicular bodies biogenesis and is a critical target of the mitogen-activated protein kinases MPK3 and MPK6 and plays an important role in the plant immune system. Disruption of LIP5 causes compromised tolerance to both heat and salt stresses. When compared with wild-type plants, lip5 mutants accumulate increased levels of ubiquitinated protein aggregates and NaCl under heat and salt stresses, respectively. LIP5 is regulated by phosphorylation, overview. Mutation of MPK phosphorylation sites in LIP5 does not affect its interaction with SKD1 but reduces its stability and, as a result, compromises its ability to complement the basal resistance of the lip5 mutants 734975
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6more activity is dependent upon hexamerisation 688690
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6more binding of substrates to the central pore of the Vps4 ATPase is activated by microtubule interacting and trafficking interacting motifs (MIMs) 734303
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6more Ist1, Did2, Vta1 and Vps60 function as a regulatory system that ensures proper recruitment and assembly of ATPase Vps4 on the ESCRT-III protein complex. Directly or indirectly these factors affect ATPase activity of Vps4, suggesting that they also regulate the Vps4 ESCRT-III disassembly activity 724447
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6more SKD1 E Vps proteins SBP1 and mVps2 interact with SKD1 656346
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6more the protein VCIP135 is essential for p97/p47-mediated membrane fusion 656341
Display the word mapDisplay the reaction diagram Show all sequences 3.6.4.6more Vps4p directly binds Vps20p and Vta1p in vitro 656345
Results 1 - 10 of 14 > >>