EC Number |
Activating Compound |
Reference |
---|
3.4.21.38 | alpha-kallikrein |
- |
753067 |
3.4.21.38 | Dextran |
dextran-mediated activation and autoactivation |
95416 |
3.4.21.38 | ellagic acid |
activation of factor XII by negatively charged agents, e.g. ellagic acid, is not necessarily accompanied by molecular scission |
95413 |
3.4.21.38 | High molecular weight kininogen |
- |
732404 |
3.4.21.38 | Kallikrein |
mediates activation of the zymogen FXII |
709176 |
3.4.21.38 | kaolin |
- |
699180 |
3.4.21.38 | kaolin |
required for maximal activity |
95410 |
3.4.21.38 | long-chain polyphosphate |
- |
732404 |
3.4.21.38 | more |
a sulfated galactan with the repeated structure -4-alpha-D-Gal-p-1->3-beta-D-Gal-p-1-> from Botryocladia accidentalis induces factor XII activation, dextran sulfates with molecular size above 8 kDa also activate factor XII |
701286 |
3.4.21.38 | more |
as with heparin, sulfated galactan from Gelidium crinale does not activate factor XII, while the polysaccharide from Botryocladia accidentalis activates factor XII in high concentrations |
701287 |