EC Number |
Activating Compound |
Reference |
---|
3.1.4.54 | 1,2-dihexanoyl-glycero-3-(hexanoylamino)propylphosphonate |
i.e. AHP-57, a phosphonic acid, activates 1.9fold at 1 mM |
708110 |
3.1.4.54 | 1,2-dioleoylphosphatidylcholine |
0.1 mM, 1.3fold stimulation |
710098 |
3.1.4.54 | 1,2-dioleoylphosphatidylethanolamine |
0.1 mM, increases activity with N-palmitoylphosphatidylamine (0.025 mM) 3.3fold, increases activity with N-arachidonoylphosphatidylamine (0.025 mM), N-oleoylphosphatidylamine (0.025 mM) and N-stearoylphosphatidylamine (0.025 mM), 2.6-2.7fold |
710098 |
3.1.4.54 | 1,2-dipalmitoylphosphatidylcholine |
0.1 mM, 1.3fold stimulation |
710098 |
3.1.4.54 | 1,2-dipalmitoylphosphatidylethanolamine |
- |
710098 |
3.1.4.54 | 15-hydroxy-N-arachidonoylethanolamine |
0.005 mM, activation to 145% of the control |
707099 |
3.1.4.54 | cardiolipin |
from bovine liver, activates by 68% at 1 mM |
708110 |
3.1.4.54 | deoxycholate |
presence of deoxycholate stabilizes the enzyme dimer and increases the catalytic activity with EC50 value of 0.186 mM. Binding is rapid and reversible |
752275 |
3.1.4.54 | methyl-1,2-dihexanoyl-glycero-3-(hexanoylamino)propylphosphonate |
i.e. AHP-38, a methylphosphonate, activates 68% at 1 mM |
708110 |
3.1.4.54 | methyl-1,2-dihexanoyl-glycero-3-(tetradecanoylamino)propylphosphonate |
i.e. AHP-36, a methylphosphonate, activates 2fold at 1 mM |
708110 |