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Activating Compound
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3.1.21.10
PCNA protein
Holliday junction-resolving enzyme Hjc interacts physically with PCNA via a canonical C-terminal PIP motif. This interaction stimulates the junction cleavage activity of Hjc in vitro. PCNA is a toroidal protein that acts as a processivity factor for many proteins. In Sulfolobus solfataricus, PCNA is a heterotrimer that can function as a molecular toolbelt, forming simultaneous interactions with up to three partner proteins with related functions in a DNA-processing pathway
725701
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