EC Number |
Activating Compound |
Reference |
---|
2.7.7.49 | betapapillomavirus E6 protein 16E6 |
activates telomerase, NFX1-91 protein is important for telomerase activation by betapapillomavirus E6 protein 16E6 |
693914 |
2.7.7.49 | betapapillomavirus E6 protein 38E6 |
activates telomerase |
693914 |
2.7.7.49 | betapapillomavirus E6 protein E6AP |
important for telomerase activation by betapapillomavirus E6 protein 16E6 |
693914 |
2.7.7.49 | borano-3TCTP |
alpha-Boranophosphate nucleoside analogs enhance 38fold the binding of Mg2+ ions to the active site of the enzyme-DNA-dNTP complex and alleviate the requirement of critical amino acids involved in phosphodiester bond formation |
662425 |
2.7.7.49 | borano-dTTP |
100fold decrease in polymerase activity caused by the R72A substitution is restored to wild-type levels using borano-dTTP. alpha-Boranophosphate nucleoside analogs enhance 38fold the binding of Mg2+ ions to the active site of the enzyme-DNA-dNTP complex and alleviate the requirement of critical amino acids involved in phosphodiester bond formation |
662425 |
2.7.7.49 | dithiothreitol |
- |
643410 |
2.7.7.49 | dithiothreitol |
maximal incorporation of dTTP into poly(rA) template primed with oligo(dT)12 with 10 mM dithiothreitol |
643447 |
2.7.7.49 | dithiothreitol |
strong stimulation |
643410 |
2.7.7.49 | dithiothreitol |
sulfhydryl reagents required for optimal activity: dithiothreitol or 2-mercaptoethanol |
643418 |
2.7.7.49 | dithiothreitol |
to observe full activity of the enzyme, it is necessary to treat the virions with a non-ionic detergent. If the treatment is at 40°C the presence of dithiothreitol is necessary to recover activity |
643411 |