EC Number   |
Activating Compound |
Reference |
|---|
   1.4.4.2 | 2-mercaptoethanol |
thiol compound required for maximal activity on glycine-CO2 exchange reaction |
391989 |
| 1.4.4.2 | dithiothreitol |
P and H protein alone jointly catalyze the glycine-CO2 exchange reaction in presence of pyridoxal phosphate and dithiothreitol |
391979 |
| 1.4.4.2 | dithiothreitol |
thiol compound required for maximal activity on glycine-CO2 exchange reaction |
391989 |
| 1.4.4.2 | GSH |
thiol compound required for maximal activity on glycine-CO2 exchange reaction |
391989 |
| 1.4.4.2 | H-protein |
upon addition of exogenous unlipoylated H-protein, kcat increases 190fold, in the absence of the lipoic acid moiety on H-protein, the methylamine adduct with pyridoxal 5'-phosphate (aminomethyl-quinonoid intermediate) is released as the product of the GLDC-catalyzed decarboxylation of glycine |
741906 |
| 1.4.4.2 | lipoylated H-protein |
the presence of the lipoyl moiety on H-protein does not affect the rates of GLDC (or GLDCcoexp)-catalyzed glycine decarboxylation |
741906 |
| 1.4.4.2 | more |
the presence of the lipoyl moiety on H-protein does not affect the rates of GLDC (or GLDCcoexp)-catalyzed glycine decarboxylation further corroborates the suggestion that H-protein (or lipoylated H-protein) does not directly participate in and is not required for release of CO2 from glycine in the formation of the pyridoxal 5'-phosphate-quinonoid intermediate, an important distinction that is contrary to earlier findings |
741906 |
