EC Number   |
Activating Compound |
Reference |
|---|
    1.14.14.23 | 2,4,6-trihydroxyacetophenone |
CYP7A1 induction, 166%, and activation, 160%, by 2,4,6-trihydroxyacetophenone, which also antagonizes the inhibition of CYP7A1 expression by chenodeoxycholic acid |
673456 |
| 1.14.14.23 | dithiothreitol |
- |
659806 |
| 1.14.14.23 | more |
a protein purified from rat liver cytosol with minumum molecular weight of 25000 stimulates cholesterol 7alpha-hydroxylase activity in presence of glutathione or thioredoxin |
285308 |
| 1.14.14.23 | more |
enzyme expression is induced by cholesterol, bile acids, cytokines, steroid hormones, and thyroid hormone |
675996 |
| 1.14.14.23 | Thiol-containing substances |
e.g. mercaptoethanol, dithiothreitol or cysteamine enhance activity |
285299 |
| 1.14.14.23 | Triton X-100 |
stimulates |
285305 |
