EC Number   |
Activating Compound |
Reference |
|---|
    1.1.1.34 | dithiothreitol |
2 mM |
286568 |
| 1.1.1.34 | DTT |
- |
740956 |
| 1.1.1.34 | EDTA |
increases the apparent HMGR activity in sweet potato extracts |
740956 |
| 1.1.1.34 | more |
4fold enzyme induction by root cutting within 2 h, and strong induction by infection with Phytophtora infestans, maximal 66fold after 2 h, induction mechanism |
655032 |
| 1.1.1.34 | more |
about 40fold enzyme induction by root cutting within 14 h, and about 875fold induction by infection with Phytophtora infestans after 22 h, induction mechanism |
655032 |
| 1.1.1.34 | more |
leaf tissue of Artemisia annua transgenic lines possess significantly higher HMGR activity compared with wild-type controls, and this activity is associated exclusively with microsomal membranes and with higher artemisinin content (increase of up to 22.5% artemisin in content compared with wild-type control Artemisia annua plants) |
700852 |
| 1.1.1.34 | more |
phosphorylation of HMGCR is stimulated by SMase C or exogenous ceramide |
695855 |
| 1.1.1.34 | more |
the activity of microsomal isoyzme Hmg2 is highest under hypo-saline and extremely hyper-saline conditions, and down-regulated under optimal growth conditions |
686736 |
| 1.1.1.34 | myristic acid |
stimulates translation of the enzyme about 1.8fold at 0.15 mM, upregulation |
655507 |
| 1.1.1.34 | squalestatin |
leads to a significant concentration-dependent activation of HMGR of ca. 3fold the activity in untreated plants. Maximal HMGR activation at 0.06 mM squalestatin. No relevant changes in the level of expression of the HMG genes or in the amount of HMGR protein |
700682 |
