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Results 1 - 10 of 12 > >>
EC Number
Activating Compound
Commentary
Reference
1,3-dimercaptopropanol
activates at 0.01 M
cysteine
activates at 0.01 M
dithiothreitol
maxmimum activity in the presence of 1 mM dithiothreitol
hydrogen sulfide
activates at 0.01 M
more
not significant efects: NADH, ATP, phosphoenol pyruvate and aspartate, even at concentrations as high as 10 mM
NH4Cl
3fold stimulation at 40 mM. No significant increase in activity above 40 mM; maximal stimulation at 40 mM, 3fold
PPIB
cytoplasmic cytophilin, interaction with phosphate acetyltransferase leads to enhanced activity and alteration in Km value. PPIase activity is not essential for these interactions, as PPIB F99A active site mutant still interacts with phosphate acetyltransferase, but PPIB activity is responsible for the observed phosphate acetyltransferase activity enhancement; cytoplasmic cytophilin, interaction with phosphate acetyltransferase leads to enhanced activity and alteration in Km value. PPIase activity is not essential for these interactions, as PPIB F99A active site mutant still interacts with phosphate acetyltransferase, but PPIB activity is responsible for the observed phosphate acetyltransferase activity enhancement
pyruvate
-
pyruvate
156% of activation at 5 mM
pyruvate
isoform PtaII has 133% activity in the presence of 0.05 mM pyruvate
Results 1 - 10 of 12 > >>