EC Number   |
Activating Compound |
Reference |
|---|
   3.6.5.6 | glycerol |
induces polymerization |
644208 |
| 3.6.5.6 | Gsalpha |
Gsalpha facilitates GTP hydrolysis on tubulin, which leads to microtubule depolymerization by increased GTPase activation on tubulin |
685385 |
| 3.6.5.6 | more |
alpha-tubulin is a GTPase activating protein that stimulates GTP hydrolysis in beta-tubulin, alpha-tubulin mutants D252A and E255A create create poisonous proteins that cause lethality, micrtubule dynamics cease |
656756 |
| 3.6.5.6 | more |
N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxybenzenesulfonamide and N-(3-fluoro-4-methoxyphenyl)pentafluorobenzenesulfonamide are unable to modulate GTPase activity of tubulin |
669786 |
| 3.6.5.6 | nocodazole |
induced by this antimitotic drug, GTP hydrolysis rate stimulated four-to fivefold |
644206 |
| 3.6.5.6 | quercetin |
0.05 mM, stimulates GTPase activity about 8fold, but inhibits polymerization of microtubules and specifically inhibits colchicine binding to tubulin |
654625 |
| 3.6.5.6 | sodium glutamate |
cosolvent stabilizes tubulin |
644203 |
| 3.6.5.6 | stathmin-like domains |
- |
685083 |
| 3.6.5.6 | sucrose |
cosolvent stabilizes tubulin |
644203 |
| 3.6.5.6 | tubulin folding cofactor |
GTPase activating proteins A, B, C and D |
644210 |
