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EC Number	Activating Compound	Commentary	Reference
1.14.15.6	Phospholipid	P-450scc reconstituted in vesicles, cholate-solubilized for small unilamellar dioleoylphosphatidylcholine vesicles, non-ionic detergent n-octyl glucoside used for large ones	285420
1.14.15.6	Runx2	activation of CYP11A1 by the osteogenic transcription factor Runx2 may contribute to attenuation of osteoblast growth. Runx2 binds to the CYP11A1 gene promoter, CYP11A1 is a direct target of Runx2	705739
1.14.15.6	Runx2	activation of CYP11A1 by the osteogenic transcription factor Runx2 may contribute to attenuation of osteoblast growth. Runx2 binds to the CYP11A1 gene promoter, CYP11A1 is a direct target of Runx2. Runx2 is rate limiting for CYP11A1 gene expression during differentation along the osteoblastic lineage	705739
1.14.15.6	Triton X-100	effect onto P-450 itself suggested	285416
1.14.15.6	Tween 20	-	285416
1.14.15.6	Tween 20	small stabilizing and binding activating effect on ternary complex of adrenodoxin-cholesterol-P-450scc	285413

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Release 2023.1 (January 2023)