EC Number   |
Activating Compound |
Reference |
|---|
    1.14.15.6 | more |
activator of cholesterol side-chain cleavage isolated from the cytosol of bovine adrenal cortex |
285426 |
| 1.14.15.6 | more |
enzymatic activity is greatest at low ionic strength with a number of different ions |
285427 |
| 1.14.15.6 | more |
enzyme induction by gonadotropic stimuli, e.g. artificially by a salmon piuitary homogenate, in ovary |
675689 |
| 1.14.15.6 | more |
head and fatty acid groups have large effects on stimulation of activity, head group appears as major determinant of the lipid interaction with the P-450scc, 1-2 and 3-4 molecules of cardiolipin and the branched phosphatidylcholines, respectively, bind highly specific to P-450scc at an effector site distant from cholesterol binding site with a resultant stabilization of an optimal cholesterol-binding conformation of P-450scc |
285429 |
| 1.14.15.6 | more |
luteinizing hormone, progesterone, and prostaglandin E2 induce enzyme expression in luteal cells |
676926 |
| 1.14.15.6 | more |
P450scc induction by available nutrients and phytoplankton blooms |
687991 |
| 1.14.15.6 | more |
vitamin D3 and cholesterol are metabolized with comparable efficiencies in cyclodextrin, but the Km for both show a strong dependence on the cyclodextrin concentration, decreasing with decreasing cyclodextrin |
704039 |
| 1.14.15.6 | octyl glucoside |
high concentrations of this detergent cause 50% stimulation of cholesterol side-chain-cleavage in large unilamellar vesicles at low cholesterol concentration, 0.01 mM increase the proportion of P-450 bound by cholesterol |
285420 |
| 1.14.15.6 | Phospholipid |
cholesterol gains access to the cytochrome within micelles |
285413 |
| 1.14.15.6 | Phospholipid |
inclusion of P-450 into vesicles |
285414 |
