2.4.2.17	A249T	the mutant is more resistant towards inhibition by L-histidine compared to the wild type enzyme	736541	
2.4.2.17	A270D	the mutant with reduced activity is more resistant towards inhibition by L-histidine compared to the wild type enzyme	736541	
2.4.2.17	A270P	conserved residue	721765	
2.4.2.17	C115A	the mutant shows reduced activity compared to the wild type enzyme	-, 778695	
2.4.2.17	C115S	the mutant shows 117fold reduced activity compared to the wild type enzyme	-, 778695	
2.4.2.17	D155A	slight increase in kcat, 3.9fold increase in KM-value for 5-phospho-alpha-D-ribose 1-diphosphate, 1.7fold increase in Km-value for ATP	678174	
2.4.2.17	D179A	the mutant shows reduced activity compared to the wild type enzyme	-, 778695	
2.4.2.17	D179N	the mutant shows reduced activity compared to the wild type enzyme	-, 778695	
2.4.2.17	D213N	the mutant is more resistant towards inhibition by L-histidine compared to the wild type enzyme	-, 736541	
2.4.2.17	E130A	site-directed mutagenesis, about 60% reduced activity compared to the wild-type enzyme, no inhibition by histidine	659495