2.7.1.154	Acute Lung Injury	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11714830&form=6&db=m	Involvement of phosphoinositide 3-kinases in neutrophil activation and the development of acute lung injury.	causal interaction,unassigned	3,0	
2.7.1.154	Arthritis, Rheumatoid	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24244039&form=6&db=m	Novel phosphoinositide 3-kinase ?,? inhibitor: potent anti-inflammatory effects and joint protection in models of rheumatoid arthritis.	causal interaction,ongoing research,therapeutic application,unassigned	2,3,4,0	
2.7.1.154	Arthritis, Rheumatoid	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24262886&form=6&db=m	Discovery of N-{5-[3-(3-hydroxypiperidin-1-yl)-1,2,4-oxadiazol-5-yl]-4-methyl-1,3-thiazol-2-yl}acetamide (TASP0415914) as an orally potent phosphoinositide 3-kinase ? inhibitor for the treatment of inflammatory diseases.	causal interaction,therapeutic application,unassigned	4,4,0	
2.7.1.154	Asthma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20148286&form=6&db=m	Consensus model for identification of novel PI3K inhibitors in large chemical library.	causal interaction,therapeutic application,unassigned	4,4,0	
2.7.1.154	Asthma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20351038&form=6&db=m	Phosphoinositide 3-kinase {delta} inhibitor suppresses IL-17 expression in a murine asthma model.	causal interaction,ongoing research,therapeutic application,unassigned	4,1,3,0	
2.7.1.154	Asthma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27556731&form=6&db=m	Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling by the PI3K inhibitor LY294002.	causal interaction,ongoing research,therapeutic application,unassigned	1,4,1,0	
2.7.1.154	Asthma	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29651336&form=6&db=m	PI3K, p38 and JAK/STAT signalling in bronchial tissue from patients with asthma following allergen challenge.	causal interaction,diagnostic usage,ongoing research,therapeutic application	2,3,4,2	
2.7.1.154	Autoimmune Diseases	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16789742&form=6&db=m	Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.	causal interaction,therapeutic application,unassigned	2,3,0	
2.7.1.154	Autoimmune Diseases	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19689378&form=6&db=m	Small molecule inhibitors of phosphoinositide 3-kinase (PI3K) delta and gamma.	causal interaction,therapeutic application,unassigned	4,4,0	
2.7.1.154	Autoimmune Diseases	http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24735732&form=6&db=m	PI3K inhibitors as potential therapeutics for autoimmune disease.	causal interaction,therapeutic application,unassigned	4,4,0