3.1.11.2 Acquired Immunodeficiency Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12367650&form=6&db=m Novel mutations in the thymidine kinase and DNA polymerase genes of acyclovir and foscarnet resistant herpes simplex viruses infecting an immunocompromised patient. causal interaction,ongoing research,therapeutic application,unassigned 1,1,1,0 3.1.11.2 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28943952&form=6&db=m miRNA biogenesis-associated RNase III nucleases Drosha and Dicer are upregulated in colorectal adenocarcinoma. causal interaction,unassigned 4,0 3.1.11.2 African Swine Fever http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8623526&form=6&db=m Evolutionary relationships among large double-stranded DNA viruses that infect microalgae and other organisms as inferred from DNA polymerase genes. ongoing research,unassigned 2,0 3.1.11.2 Alzheimer Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34528746&form=6&db=m p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease. causal interaction,unassigned 4,0 3.1.11.2 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22869729&form=6&db=m ERK1/2 activation is a therapeutic target in age-related macular degeneration. causal interaction,therapeutic application,unassigned 4,4,0 3.1.11.2 Bloom Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28279982&form=6&db=m A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1. causal interaction,ongoing research,therapeutic application,unassigned 3,3,3,0 3.1.11.2 Brain Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20551246&form=6&db=m Genomic analysis of the 55 kDa subunit of DNA polymerase epsilon in human intracranial neoplasms. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,4,0 3.1.11.2 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12713808&form=6&db=m The expression of Exonuclease III from E. coli in mitochondria of breast cancer cells diminishes mitochondrial DNA repair capacity and cell survival after oxidative stress. causal interaction,ongoing research,unassigned 1,3,0 3.1.11.2 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19129559&form=6&db=m Genomic changes of the 55 kDa subunit of DNA polymerase epsilon in human breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,2,4,0 3.1.11.2 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8819107&form=6&db=m Potential role of DNA polymerase beta in gene therapy against cancer: a case for colorectal cancer. causal interaction,diagnostic usage,therapeutic application,unassigned 4,4,4,0