2.5.1.21 Acidosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9503410&form=6&db=m [Inhibitory action of natural compounds of microbial origin on cholesterol metabolism] therapeutic application,unassigned 1,0 2.5.1.21 Acquired Immunodeficiency Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10669567&form=6&db=m Successful virtual screening of a chemical database for farnesyltransferase inhibitor leads. causal interaction,therapeutic application,unassigned 2,4,0 2.5.1.21 Acute Lung Injury http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22949548&form=6&db=m Streptococcal M1 protein triggers farnesyltransferase-dependent formation of CXC chemokines in alveolar macrophages and neutrophil infiltration in the lung. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 2.5.1.21 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9770500&form=6&db=m A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 2.5.1.21 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12663718&form=6&db=m Phase II and pharmacodynamic study of the farnesyltransferase inhibitor R115777 as initial therapy in patients with metastatic pancreatic adenocarcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,3,2,4 2.5.1.21 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17348444&form=6&db=m Expression of PTEN and FHIT is involved in regulating the balance between apoptosis and proliferation in lung carcinomas. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,4,4,1 2.5.1.21 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22272079&form=6&db=m Enhanced Antiproliferative and Apoptotic Response of HT-29 Adenocarcinoma Cells to Combination of Photoactivated Hypericin and Farnesyltransferase Inhibitor Manumycin A. ongoing research,therapeutic application,unassigned 2,3,0 2.5.1.21 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31677963&form=6&db=m The diagnostic utility of zinc E-box 1 (ZEB1) transcription factor for identification of pulmonary sarcomatoid carcinoma in cytologic and surgical specimens. diagnostic usage,therapeutic application,unassigned 3,2,0 2.5.1.21 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10607742&form=6&db=m Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. causal interaction,ongoing research,therapeutic application,unassigned 4,4,4,0 2.5.1.21 Adenoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33307558&form=6&db=m Role of the Mevalonate Pathway in Adrenocortical Tumorigenesis. causal interaction,ongoing research,unassigned 3,1,0