1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15865448&form=6&db=m Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids. causal interaction,unassigned 2,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16269441&form=6&db=m Retinal degeneration associated with RDH12 mutations results from decreased 11-cis retinal synthesis due to disruption of the visual cycle. causal interaction,unassigned 4,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17130236&form=6&db=m Targeted disruption of the murine retinal dehydrogenase gene Rdh12 does not limit visual cycle function. causal interaction,unassigned 3,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17197551&form=6&db=m RDH12 and RPE65, visual cycle genes causing leber congenital amaurosis, differ in disease expression. causal interaction,unassigned 3,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17512723&form=6&db=m RDH12, a retinol dehydrogenase causing Leber's congenital amaurosis, is also involved in steroid metabolism. causal interaction,unassigned 3,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18326732&form=6&db=m Retinol dehydrogenases RDH11 and RDH12 in the mouse retina: expression levels during development and regulation by oxidative stress. causal interaction,unassigned 3,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22621924&form=6&db=m Reduction of all-trans-retinal in vertebrate rod photoreceptors requires the combined action of RDH8 and RDH12. causal interaction,unassigned 3,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28540421&form=6&db=m Yeast ENV9 encodes a conserved lipid droplet (LD) short-chain dehydrogenase involved in LD morphology. causal interaction,unassigned 4,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32855876&form=6&db=m Report from a Workshop on Accelerating the Development of Treatments for Inherited Retinal Dystrophies Associated with Mutations in the RDH12 Gene. causal interaction,unassigned 3,0 1.1.1.105 Blindness http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33928237&form=6&db=m Retinal imaging in inherited retinal diseases. causal interaction,unassigned 1,0