2.4.99.6 Abortion, Habitual http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34135905&form=6&db=m Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 2.4.99.6 Abortion, Spontaneous http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34135905&form=6&db=m Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,2,0 2.4.99.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20824144&form=6&db=m alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23726834&form=6&db=m ?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 2.4.99.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24878505&form=6&db=m Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of ?2?1 integrin and E-cadherin function. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 2.4.99.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32872308&form=6&db=m Knockdown of ?2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion. causal interaction,therapeutic application,unassigned 4,4,0 2.4.99.6 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33598419&form=6&db=m ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 2.4.99.6 Autoimmune Diseases http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22257379&form=6&db=m The expanding role of ?2-3 sialylation for leukocyte trafficking in vivo. causal interaction,therapeutic application,unassigned 1,4,0 2.4.99.6 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9751611&form=6&db=m Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in human breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 2.4.99.6 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10683317&form=6&db=m Regulation of sialyltransferase expression by estradiol and 4-OH-tamoxifen in the human breast cancer cell MCF-7. causal interaction,diagnostic usage,ongoing research,unassigned 2,2,4,0 2.4.99.6 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12841680&form=6&db=m Prognostic value of tumoral sialyltransferase expression and circulating E-selectin concentrations in node-negative breast cancer patients. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,1,0 2.4.99.6 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27779707&form=6&db=m ST3Gal III modulates breast cancer cell adhesion and invasion by altering the expression of invasion-related molecules. causal interaction,therapeutic application,unassigned 2,1,0 2.4.99.6 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33598419&form=6&db=m ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 2.4.99.6 Carcinogenesis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12787925&form=6&db=m Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays. causal interaction,diagnostic usage,unassigned 4,1,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8611500&form=6&db=m Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line. ongoing research,unassigned 3,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9343936&form=6&db=m Cloning and expression of SAT-3 involved in SA-Le(x) biosynthesis: inhibition studies with polyclonal antibody against GST-SAT-3 fusion protein. causal interaction,ongoing research,unassigned 2,1,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9690558&form=6&db=m Up-regulation of a set of glycosyltransferase genes in human colorectal cancer. diagnostic usage,ongoing research,unassigned 3,4,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10434038&form=6&db=m Altered mRNA expression of glycosyltransferases in human gastric carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,4,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10673297&form=6&db=m Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,2,1 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11585423&form=6&db=m Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12079299&form=6&db=m Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,4,3,1 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12375029&form=6&db=m Clinical significance of ST3Gal IV expression in human renal cell carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18485915&form=6&db=m DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer. ongoing research,therapeutic application,unassigned 1,3,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23799130&form=6&db=m Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31695778&form=6&db=m Carcinoembryonic antigen carrying SLeX as a new biomarker of more aggressive gastric carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31747460&form=6&db=m "Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression". causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 2.4.99.6 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33598419&form=6&db=m ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4 2.4.99.6 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17054948&form=6&db=m Interleukin-1beta induces sialyl Lewis X on hepatocellular carcinoma HuH-7 cells via enhanced expression of ST3Gal IV and FUT VI gene. ongoing research,unassigned 2,0 2.4.99.6 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21147760&form=6&db=m Differences in CD75s- and iso-CD75s-ganglioside content and altered mRNA expression of sialyltransferases ST6GAL1 and ST3GAL6 in human hepatocellular carcinomas and nontumoral liver tissues. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 2.4.99.6 Carcinoma, Hepatocellular http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27906498&form=6&db=m Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway. ongoing research,unassigned 1,0 2.4.99.6 Carcinoma, Renal Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12375029&form=6&db=m Clinical significance of ST3Gal IV expression in human renal cell carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 2.4.99.6 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11585423&form=6&db=m Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Carcinoma, Squamous Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12079299&form=6&db=m Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,4,3,1 2.4.99.6 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1312899&form=6&db=m Sialyltransferase activity and hepatic tumor growth in a nude mouse model of colorectal cancer metastases. diagnostic usage,ongoing research,unassigned 3,4,0 2.4.99.6 Colorectal Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9690558&form=6&db=m Up-regulation of a set of glycosyltransferase genes in human colorectal cancer. diagnostic usage,ongoing research,unassigned 3,4,0 2.4.99.6 Congenital, Hereditary, and Neonatal Diseases and Abnormalities http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31584066&form=6&db=m A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9. unassigned - 2.4.99.6 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25066807&form=6&db=m Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 2.4.99.6 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31584066&form=6&db=m A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9. unassigned - 2.4.99.6 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33440761&form=6&db=m Congenital Disorders of Glycosylation from a Neurological Perspective. causal interaction,unassigned 1,0 2.4.99.6 Epilepsy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34022416&form=6&db=m Phenotype of ST3GAL3 deficient patients: A case and review of the literature. causal interaction,unassigned 4,0 2.4.99.6 Epilepsy, Temporal Lobe http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25066807&form=6&db=m Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 2.4.99.6 Hypertension, Pulmonary http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14705225&form=6&db=m Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in peripheral blood mononuclear cells in systemic sclerosis. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 2.4.99.6 Influenza in Birds http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23943396&form=6&db=m The expression pattern and histological distribution of sialyltransferases ST3Gal III in yellow chicken. unassigned - 2.4.99.6 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21907012&form=6&db=m ST3GAL3 mutations impair the development of higher cognitive functions. causal interaction,unassigned 1,0 2.4.99.6 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32666583&form=6&db=m A novel variant of ST3GAL3 causes non-syndromic autosomal recessive intellectual disability in Iranian patients. causal interaction,unassigned 3,0 2.4.99.6 Intellectual Disability http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34022416&form=6&db=m Phenotype of ST3GAL3 deficient patients: A case and review of the literature. causal interaction,unassigned 4,0 2.4.99.6 Leukemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9884401&form=6&db=m UDP-GlcNAc:Galbeta1-->3GalNAc (GlcNAc to GalNAc) beta1-->6N-acetylglucosaminyltransferase holds a key role on the control of CD15s expression in human pre-B lymphoid cell lines. diagnostic usage,ongoing research,unassigned 3,3,0 2.4.99.6 Leukemia, Myelogenous, Chronic, BCR-ABL Positive http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28512058&form=6&db=m Downregulation of miR-224 and let-7i contribute to cell survival and chemoresistance in chronic myeloid leukemia cells by regulating ST3GAL IV expression. causal interaction,unassigned 1,0 2.4.99.6 Lymphatic Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12079299&form=6&db=m Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,4,3,1 2.4.99.6 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8611500&form=6&db=m Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line. ongoing research,unassigned 3,0 2.4.99.6 Melanoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10206952&form=6&db=m Molecular cloning of a novel alpha2,3-sialyltransferase (ST3Gal VI) that sialylates type II lactosamine structures on glycoproteins and glycolipids. ongoing research,unassigned 4,0 2.4.99.6 Mouth Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31747460&form=6&db=m "Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression". causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 2.4.99.6 Multiple Myeloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25061176&form=6&db=m The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma. causal interaction,diagnostic usage,therapeutic application,unassigned 1,3,1,0 2.4.99.6 Multiple Myeloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27148485&form=6&db=m Targeting Selectins and Their Ligands in Cancer. causal interaction,unassigned 4,0 2.4.99.6 Multiple Myeloma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33649796&form=6&db=m lncRNA ST3GAL6?AS1 promotes invasion by inhibiting hnRNPA2B1?mediated ST3GAL6 expression in multiple myeloma. causal interaction,unassigned 2,0 2.4.99.6 n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12097641&form=6&db=m Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands. causal interaction,unassigned 3,0 2.4.99.6 n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23252400&form=6&db=m West syndrome caused by ST3Gal-III deficiency. causal interaction,ongoing research,unassigned 4,2,0 2.4.99.6 n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30089820&form=6&db=m A patient-specific induced pluripotent stem cell model for West syndrome caused by ST3GAL3 deficiency. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,4,0 2.4.99.6 n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32380539&form=6&db=m The sialyltransferase ST3Gal-IV guides murine T-cell progenitors to the thymus. causal interaction,unassigned 2,0 2.4.99.6 n-acetyllactosaminide alpha-2,3-sialyltransferase deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34022416&form=6&db=m Phenotype of ST3GAL3 deficient patients: A case and review of the literature. causal interaction,unassigned 4,0 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12079299&form=6&db=m Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,4,3,1 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12787925&form=6&db=m Glycosyltransferase expression in human colonic tissue examined by oligonucleotide arrays. causal interaction,diagnostic usage,unassigned 4,1,0 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15138129&form=6&db=m Correlation of glycosyltransferases mRNA expression in extrahepatic bile duct carcinoma with clinical pathological characteristics. causal interaction,diagnostic usage,unassigned 3,3,0 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20824144&form=6&db=m alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23726834&form=6&db=m ?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31747460&form=6&db=m "Aberrant sialylation plays a significant role in oral squamous cell carcinoma progression". causal interaction,diagnostic usage,ongoing research,unassigned 4,4,4,0 2.4.99.6 Neoplasm Metastasis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32872308&form=6&db=m Knockdown of ?2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion. causal interaction,therapeutic application,unassigned 4,4,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9751611&form=6&db=m Multiplex reverse transcription polymerase chain reaction assessment of sialyltransferase expression in human breast cancer. causal interaction,diagnostic usage,ongoing research,unassigned 4,4,3,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10673297&form=6&db=m Altered mRNA expression of glycosyltransferases in human colorectal carcinomas and liver metastases. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,2,1 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12375029&form=6&db=m Clinical significance of ST3Gal IV expression in human renal cell carcinoma. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12841680&form=6&db=m Prognostic value of tumoral sialyltransferase expression and circulating E-selectin concentrations in node-negative breast cancer patients. diagnostic usage,ongoing research,therapeutic application,unassigned 4,4,1,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12931020&form=6&db=m Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15138129&form=6&db=m Correlation of glycosyltransferases mRNA expression in extrahepatic bile duct carcinoma with clinical pathological characteristics. causal interaction,diagnostic usage,unassigned 3,3,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20824144&form=6&db=m alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21147760&form=6&db=m Differences in CD75s- and iso-CD75s-ganglioside content and altered mRNA expression of sialyltransferases ST6GAL1 and ST3GAL6 in human hepatocellular carcinomas and nontumoral liver tissues. diagnostic usage,ongoing research,therapeutic application,unassigned 1,2,1,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21447973&form=6&db=m Correlation between Heterogeneous Expression of Sialyltransferases and MUC16 in Ovarian Tumor Tissues. causal interaction,ongoing research,unassigned 4,2,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22257379&form=6&db=m The expanding role of ?2-3 sialylation for leukocyte trafficking in vivo. causal interaction,therapeutic application,unassigned 1,4,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23726834&form=6&db=m ?2,3-sialyltransferase ST3Gal IV promotes migration and metastasis in pancreatic adenocarcinoma cells and tends to be highly expressed in pancreatic adenocarcinoma tissues. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23799130&form=6&db=m Expression of ST3GAL4 leads to SLe(x) expression and induces c-Met activation and an invasive phenotype in gastric carcinoma cells. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,4,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24878505&form=6&db=m Pancreatic cancer cell glycosylation regulates cell adhesion and invasion through the modulation of ?2?1 integrin and E-cadherin function. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,2,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25061176&form=6&db=m The sialyltransferase ST3GAL6 influences homing and survival in multiple myeloma. causal interaction,diagnostic usage,therapeutic application,unassigned 1,3,1,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25955084&form=6&db=m Glycosyltransferases as marker genes for the quantitative polymerase chain reaction-based detection of circulating tumour cells from blood samples of patients with breast cancer undergoing adjuvant therapy. diagnostic usage,ongoing research,unassigned 4,3,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26555707&form=6&db=m Pseudomonas aeruginosa pyocyanin modulates mucin glycosylation with sialyl-Lewis(x) to increase binding to airway epithelial cells. unassigned - 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27148485&form=6&db=m Targeting Selectins and Their Ligands in Cancer. causal interaction,unassigned 4,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27535614&form=6&db=m Unexpected distribution of CA19.9 and other type 1 chain Lewis antigens in normal and cancer tissues of colon and pancreas: Importance of the detection method and role of glycosyltransferase regulation. diagnostic usage,ongoing research,unassigned 3,3,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27871859&form=6&db=m Alpha2,3-sialyltransferase III knockdown sensitized ovarian cancer cells to cisplatin-induced apoptosis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27906498&form=6&db=m Sialyltransferase ST3GAL6 mediates the effect of microRNA-26a on cell growth, migration, and invasion in hepatocellular carcinoma through the protein kinase B/mammalian target of rapamycin pathway. ongoing research,unassigned 1,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28977470&form=6&db=m The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer. unassigned - 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=29894296&form=6&db=m Hypoxia and serum deprivation induces glycan alterations in triple negative breast cancer cells. diagnostic usage,unassigned 3,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30613961&form=6&db=m LncRNA ST3Gal6-AS1/ST3Gal6 axis mediates colorectal cancer progression by regulating ?-2,3 sialylation via PI3K/Akt signaling. causal interaction,diagnostic usage,unassigned 3,2,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31872800&form=6&db=m Siglec1-expressing subcapsular sinus macrophages provide soil for melanoma lymph node metastasis. diagnostic usage,therapeutic application,unassigned 3,1,0 2.4.99.6 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32929335&form=6&db=m Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer. causal interaction,diagnostic usage,therapeutic application,unassigned 2,3,1,0 2.4.99.6 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16112178&form=6&db=m Altered mRNA expressions of sialyltransferases in ovarian cancers. causal interaction,diagnostic usage,ongoing research,unassigned 4,1,3,0 2.4.99.6 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21447973&form=6&db=m Correlation between Heterogeneous Expression of Sialyltransferases and MUC16 in Ovarian Tumor Tissues. causal interaction,ongoing research,unassigned 4,2,0 2.4.99.6 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=27871859&form=6&db=m Alpha2,3-sialyltransferase III knockdown sensitized ovarian cancer cells to cisplatin-induced apoptosis. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 2.4.99.6 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31702036&form=6&db=m ST3Gal3 confers paclitaxel?mediated chemoresistance in ovarian cancer cells by attenuating caspase?8/3 signaling. causal interaction,ongoing research,therapeutic application,unassigned 3,3,3,0 2.4.99.6 Pancreatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20824144&form=6&db=m alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Pneumonia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23677475&form=6&db=m Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice. ongoing research,unassigned 2,0 2.4.99.6 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16300412&form=6&db=m Analysis of the specificity of sialyltransferases toward mucin core 2, globo, and related structures. identification of the sialylation sequence and the effects of sulfate, fucose, methyl, and fluoro substituents of the carbohydrate chain in the biosynthesis of selectin and siglec ligands, and novel sialylation by cloned alpha2,3(O)sialyltransferase. ongoing research,unassigned 3,0 2.4.99.6 Pterygium http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10393028&form=6&db=m Alteration of sialyl Lewis epitope expression in pterygium. causal interaction,unassigned 4,0 2.4.99.6 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11389169&form=6&db=m Differential expression of mRNAs for sialyltransferase isoenzymes induced in the hippocampus of mouse following kindled seizures. ongoing research,unassigned 1,0 2.4.99.6 Seizures http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25066807&form=6&db=m Sialyltransferase ST3Gal IV deletion protects against temporal lobe epilepsy. causal interaction,ongoing research,therapeutic application,unassigned 3,4,4,0 2.4.99.6 Spasms, Infantile http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23252400&form=6&db=m West syndrome caused by ST3Gal-III deficiency. causal interaction,ongoing research,unassigned 4,2,0 2.4.99.6 Spasms, Infantile http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30089820&form=6&db=m A patient-specific induced pluripotent stem cell model for West syndrome caused by ST3GAL3 deficiency. causal interaction,diagnostic usage,ongoing research,unassigned 3,2,4,0 2.4.99.6 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12931020&form=6&db=m Clinical relevance of sialyltransferases ST6GAL-I and ST3GAL-III in gastric cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 2.4.99.6 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18485915&form=6&db=m DNA hypermethylation contributes to incomplete synthesis of carbohydrate determinants in gastrointestinal cancer. ongoing research,therapeutic application,unassigned 1,3,0 2.4.99.6 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21140242&form=6&db=m Altered mRNA expressions of sialyltransferases in human gastric cancer tissues. causal interaction,diagnostic usage,therapeutic application,unassigned 3,4,1,0 2.4.99.6 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31695778&form=6&db=m Carcinoembryonic antigen carrying SLeX as a new biomarker of more aggressive gastric carcinomas. causal interaction,diagnostic usage,ongoing research,unassigned 1,3,4,0 2.4.99.6 Stomach Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31979110&form=6&db=m Analysis of the Effect of Increased ?2,3-Sialylation on RTK Activation in MKN45 Gastric Cancer Spheroids Treated with Crizotinib. causal interaction,ongoing research,therapeutic application,unassigned 4,3,4,0 2.4.99.6 Thrombocytopenia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12097641&form=6&db=m Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands. causal interaction,unassigned 3,0 2.4.99.6 Urinary Bladder Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32929335&form=6&db=m Identification of glycogene-type and validation of ST3GAL6 as a biomarker predicts clinical outcome and cancer cell invasion in urinary bladder cancer. causal interaction,diagnostic usage,therapeutic application,unassigned 2,3,1,0 2.4.99.6 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11585423&form=6&db=m Altered mRNA expression of sialyltransferase in squamous cell carcinomas of the cervix. causal interaction,diagnostic usage,ongoing research,unassigned 4,3,3,0 2.4.99.6 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12079299&form=6&db=m Expression of sialyltransferase family members in cervix squamous cell carcinoma correlates with lymph node metastasis. causal interaction,diagnostic usage,ongoing research,therapeutic application 2,4,3,1 2.4.99.6 Uterine Cervical Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=33598419&form=6&db=m ST3Gal IV Mediates the Growth and Proliferation of Cervical Cancer Cells In Vitro and In Vivo Via the Notch/p21/CDKs Pathway. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,4