1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11750244&form=6&db=m 5alpha-reductase activity in the prostate. causal interaction,ongoing research,therapeutic application,unassigned 4,2,1,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=835597&form=6&db=m Male pseudohermaphroditism due to steroid 5-alpha-reductase deficiency. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7554313&form=6&db=m A new deletion of the 5 alpha-reductase type 2 gene in a Turkish family with 5 alpha-reductase deficiency. causal interaction,unassigned 1,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8001864&form=6&db=m [The importance of DNA analysis in the diagnosis of steroid 5-alpha-reductase deficiency] causal interaction,diagnostic usage,unassigned 4,4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9745434&form=6&db=m Molecular characterization of 5 alpha-reductase type 2 deficiency and fertility in a Swedish family. causal interaction,unassigned 3,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11420135&form=6&db=m Molecular basis of androgen insensitivity. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11534997&form=6&db=m Androgens, androgen receptors, and male gender role behavior. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428202&form=6&db=m Disorders of androgen action. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12576851&form=6&db=m Giant seminoma in a patient with 5 alpha-reductase type 2 deficiency. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12713261&form=6&db=m A novel mutation of the 5alpha-reductase type 2 gene in two unrelated Egyptian children with ambiguous genitalia. causal interaction,diagnostic usage,unassigned 4,2,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17609295&form=6&db=m Molecular characterization of 6 unrelated Italian patients with 5alpha-reductase type 2 deficiency. causal interaction,diagnostic usage,therapeutic application,unassigned 4,3,1,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18391540&form=6&db=m Detection of the G34R mutation in the 5 alpha reductase 2 gene by allele specific PCR and its linkage to the 89L allele among Egyptian cases. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=22235201&form=6&db=m The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases. causal interaction,unassigned 1,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24885102&form=6&db=m Testicular histological and immunohistochemical aspects in a post-pubertal patient with 5 alpha-reductase type 2 deficiency: case report and review of the literature in a perspective of evaluation of potential fertility of these patients. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28110336&form=6&db=m New Territory for an Old Disease: 5-Alpha-Reductase Type 2 Deficiency in Bulgaria. causal interaction,unassigned 3,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=28544750&form=6&db=m Unexpected ethical dilemmas in sex assignment in 46,XY DSD due to 5-alpha reductase type 2 deficiency. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=31885560&form=6&db=m Characterising SRD5A2 Gene Variants in 37 Indonesian Patients with 5-Alpha-Reductase Type 2 Deficiency. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32346305&form=6&db=m Integrative and Analytical Review of the 5-Alpha-Reductase Type 2 Deficiency Worldwide. causal interaction,unassigned 4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34140259&form=6&db=m 5-Alpha-reductase type 2 deficiency. A new case in the Spanish population. causal interaction,unassigned 3,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34149847&form=6&db=m Accuracy of Urinary Etiocholanolone/Androsterone Ratio as Alternative to Serum Testosterone/Dihydrotestosterone Ratio for Diagnosis of 5 Alpha-reductase Type 2 Deficiency Patients and Carriers in Indonesia. causal interaction,diagnostic usage,unassigned 4,4,0 1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (nadp+) deficiency http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=34251982&form=6&db=m Fetal Genotype-Phenotype Sex Discordance: A Case of 5-Alpha-Reductase Deficiency. causal interaction,unassigned 4,0 1.3.1.22 Acne Vulgaris http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11314752&form=6&db=m Clinical application of 5alpha-reductase inhibitors. therapeutic application,unassigned 4,0 1.3.1.22 Acne Vulgaris http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18465521&form=6&db=m Epristeride (SmithKline Beecham). causal interaction,therapeutic application,unassigned 2,4,0 1.3.1.22 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8916360&form=6&db=m Immunochemical detection of 5 alpha-reductase in human serum. diagnostic usage,unassigned 1,0 1.3.1.22 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9506528&form=6&db=m 5alpha-reductase and 17beta-hydroxysteroid dehydrogenase expression in epithelial cells from hyperplastic and malignant human prostate. ongoing research,unassigned 4,0 1.3.1.22 Adenocarcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17010533&form=6&db=m Expression of aromatase and 5-alpha-reductase genes in endometrial adenocarcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 3,4,4,0 1.3.1.22 Alopecia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11397903&form=6&db=m 5 alpha-reductase type 2 is constitutively expressed in the dermal papilla and connective tissue sheath of the hair follicle in vivo but not during culture in vitro. causal interaction,unassigned 4,0 1.3.1.22 Alopecia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11480145&form=6&db=m Management of male pattern hair loss. causal interaction,therapeutic application,unassigned 1,4,0 1.3.1.22 Alopecia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12573818&form=6&db=m Androgens and alopecia. causal interaction,unassigned 1,0 1.3.1.22 Alopecia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24855036&form=6&db=m A pharmacogenetic survey of androgen receptor (CAG)n and (GGN)n polymorphisms in patients experiencing long term side effects after finasteride discontinuation. causal interaction,therapeutic application,unassigned 3,4,0 1.3.1.22 Androgen-Insensitivity Syndrome http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11420135&form=6&db=m Molecular basis of androgen insensitivity. causal interaction,unassigned 4,0 1.3.1.22 Azoospermia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10368476&form=6&db=m Steroid 5alpha-reductase 2 gene melting polymorphisms in male subjects with azoospermia or oligospermia. causal interaction,diagnostic usage,ongoing research,unassigned 2,4,3,0 1.3.1.22 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12100746&form=6&db=m A49T, V89L and TA repeat polymorphisms of steroid 5alpha-reductase type II and breast cancer risk in Japanese women. causal interaction,therapeutic application,unassigned 4,1,0 1.3.1.22 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14652280&form=6&db=m The V89L polymorphism in the 5-alpha-reductase type 2 gene and risk of breast cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,4,4,1 1.3.1.22 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16806904&form=6&db=m Dutasteride affects progesterone metabolizing enzyme activity/expression in human breast cell lines resulting in suppression of cell proliferation and detachment. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,1,4,4 1.3.1.22 Breast Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19171445&form=6&db=m The dialectic role of progesterone. causal interaction,diagnostic usage,unassigned 1,1,0 1.3.1.22 Carcinoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16286153&form=6&db=m Five-alpha-reductase expression in benign and malignant urothelium: correlation with disease characteristics and outcome. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.3.1.22 Carcinoma, Transitional Cell http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16286153&form=6&db=m Five-alpha-reductase expression in benign and malignant urothelium: correlation with disease characteristics and outcome. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.3.1.22 Coloboma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30019980&form=6&db=m Early-onset retinal dystrophy and chronic dermatitis in a girl with an undiagnosed congenital disorder of glycosylation (SRD5A3-CDG). causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.3.1.22 Dermatitis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30019980&form=6&db=m Early-onset retinal dystrophy and chronic dermatitis in a girl with an undiagnosed congenital disorder of glycosylation (SRD5A3-CDG). causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.3.1.22 Dermatitis, Atopic http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30019980&form=6&db=m Early-onset retinal dystrophy and chronic dermatitis in a girl with an undiagnosed congenital disorder of glycosylation (SRD5A3-CDG). causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=835597&form=6&db=m Male pseudohermaphroditism due to steroid 5-alpha-reductase deficiency. causal interaction,unassigned 4,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8110760&form=6&db=m Natural mutagenesis study of the human steroid 5 alpha-reductase 2 isozyme. causal interaction,unassigned 1,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8721983&form=6&db=m 5 alpha-reduced androgens play a key role in murine parturition. causal interaction,unassigned 3,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9208814&form=6&db=m Male pseudohermaphroditism resulting from a novel mutation in the human steroid 5 alpha-reductase type 2 gene (SRD5A2). ongoing research,unassigned 4,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11420135&form=6&db=m Molecular basis of androgen insensitivity. causal interaction,unassigned 4,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428202&form=6&db=m Disorders of androgen action. causal interaction,unassigned 4,0 1.3.1.22 Disorder of Sex Development, 46,XY http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24383016&form=6&db=m 5-alpha-reductase 2 deficiency in a woman with primary amenorrhea. causal interaction,unassigned 4,0 1.3.1.22 Dwarfism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15993049&form=6&db=m 5alpha-Reductase activity in Lycopersicon esculentum: cloning and functional characterization of LeDET2 and evidence of the presence of two isoenzymes. ongoing research,therapeutic application,unassigned 2,3,0 1.3.1.22 Endometriosis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17983420&form=6&db=m Androgen receptor and 5alpha-reductase are expressed in pelvic endometriosis. causal interaction,diagnostic usage,unassigned 4,4,0 1.3.1.22 Hirsutism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11314752&form=6&db=m Clinical application of 5alpha-reductase inhibitors. therapeutic application,unassigned 4,0 1.3.1.22 Hirsutism http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11702316&form=6&db=m Management of hirsutism. therapeutic application,unassigned 1,0 1.3.1.22 Hyperprolactinemia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18379994&form=6&db=m Effects of sulpiride on mRNA levels of steroid 5alpha-reductase isozymes in prostate of adult rats. causal interaction,unassigned 4,0 1.3.1.22 Hypospadias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10458450&form=6&db=m 5alpha-reductase type 2 mutations are present in some boys with isolated hypospadias. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,3,1 1.3.1.22 Hypospadias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11845321&form=6&db=m Expression of the androgen receptor and 5 alpha-reductase type 2 in the developing human fetal penis and urethra. causal interaction,therapeutic application,unassigned 1,1,0 1.3.1.22 Hypospadias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12428202&form=6&db=m Disorders of androgen action. causal interaction,unassigned 4,0 1.3.1.22 Hypospadias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14739525&form=6&db=m Steroid 5alpha-reductase 1 polymorphisms and testosterone/dihydrotestosterone ratio in male patients with hypospadias. causal interaction,diagnostic usage,unassigned 2,1,0 1.3.1.22 Hypospadias http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21714467&form=6&db=m Two novel mutations of SRD5A2 gene in Indonesian siblings with clinical 5-alpha-reductase deficiency. causal interaction,unassigned 4,0 1.3.1.22 Insulin Resistance http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18633104&form=6&db=m Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity. causal interaction,diagnostic usage,therapeutic application,unassigned 4,2,2,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10416833&form=6&db=m Differences in steroid 5alpha-reductase iso-enzymes expression between normal and pathological human prostate tissue. diagnostic usage,ongoing research,unassigned 4,1,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11259089&form=6&db=m Codon 89 polymorphism in the human 5 alpha-reductase gene in primary breast cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,2,1 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12659654&form=6&db=m Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells. ongoing research,unassigned 3,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14532845&form=6&db=m 5alpha-reductase type 1 immunostaining is enhanced in some prostate cancers compared with benign prostatic hyperplasia epithelium. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15212687&form=6&db=m Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma. causal interaction,diagnostic usage,ongoing research,unassigned 3,3,3,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15310997&form=6&db=m Effect of the dual 5alpha-reductase inhibitor dutasteride on markers of tumor regression in prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15538746&form=6&db=m Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,3,4 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16286153&form=6&db=m Five-alpha-reductase expression in benign and malignant urothelium: correlation with disease characteristics and outcome. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18215136&form=6&db=m Involvement of Egr-1 in HGF-induced elevation of the human 5alpha-R1 gene in human hepatocellular carcinoma cells. causal interaction,ongoing research,unassigned 4,4,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19171445&form=6&db=m The dialectic role of progesterone. causal interaction,diagnostic usage,unassigned 1,1,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19215786&form=6&db=m Association among polymorphisms in the steroid 5alpha-reductase type II (SRD5A2) gene, prostate cancer risk, and pathologic characteristics of prostate tumors in an Ecuadorian population. causal interaction,diagnostic usage,unassigned 4,1,0 1.3.1.22 Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23579488&form=6&db=m SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer. causal interaction,diagnostic usage,ongoing research,unassigned 2,4,3,0 1.3.1.22 Neoplastic Processes http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18328817&form=6&db=m Steroid 5-alpha reductase type 2 activity in biopsies from malignant and normal prostatic tissues. diagnostic usage,unassigned 4,0 1.3.1.22 Oligospermia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10368476&form=6&db=m Steroid 5alpha-reductase 2 gene melting polymorphisms in male subjects with azoospermia or oligospermia. causal interaction,diagnostic usage,ongoing research,unassigned 2,4,3,0 1.3.1.22 Optic Atrophy http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30019980&form=6&db=m Early-onset retinal dystrophy and chronic dermatitis in a girl with an undiagnosed congenital disorder of glycosylation (SRD5A3-CDG). causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.3.1.22 Ovarian Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11751447&form=6&db=m The steroid 5alpha-reductase type II TA repeat polymorphism is not associated with risk of breast or ovarian cancer in Australian women. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,4,4,1 1.3.1.22 Peripheral Arterial Disease http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19246976&form=6&db=m Polymorphisms of steroid 5-alpha-reductase type I (SRD5A1) gene are associated to peripheral arterial disease. causal interaction,ongoing research,unassigned 4,1,0 1.3.1.22 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16018939&form=6&db=m Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic hyperplasia and prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,3 1.3.1.22 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18465521&form=6&db=m Epristeride (SmithKline Beecham). causal interaction,therapeutic application,unassigned 2,4,0 1.3.1.22 Prostatic Hyperplasia http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=20823678&form=6&db=m Establishment of a novel model for studying the effects of extracts of Chinese herb medicine on human type II 5alpha-reductase in vitro. causal interaction,unassigned 4,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9067262&form=6&db=m A prevalent missense substitution that modulates activity of prostatic steroid 5alpha-reductase. unassigned - 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10688862&form=6&db=m Hormonal carcinogenesis. ongoing research,therapeutic application,unassigned 3,1,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11220660&form=6&db=m The role of molecular genetics in chemoprevention studies of prostate cancer. causal interaction,therapeutic application,unassigned 3,1,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11355945&form=6&db=m A missense substitution A49T in the steroid 5-alpha-reductase gene (SRD5A2) is not associated with prostate cancer in Finland. unassigned - 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11552710&form=6&db=m Molecular epidemiologic studies within the Selenium and Vitamin E Cancer Prevention Trial (SELECT). causal interaction,therapeutic application,unassigned 3,1,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11588134&form=6&db=m Polymorphic markers in the SRD5A2 gene and prostate cancer risk: a population-based case-control study. causal interaction,diagnostic usage,ongoing research,therapeutic application 3,3,3,1 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11927504&form=6&db=m Steroid 5-alpha reductase type II V89L substitution is not associated with risk of prostate cancer in a multiethnic population study. causal interaction,diagnostic usage,therapeutic application,unassigned 3,2,1,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14532845&form=6&db=m 5alpha-reductase type 1 immunostaining is enhanced in some prostate cancers compared with benign prostatic hyperplasia epithelium. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14716738&form=6&db=m Dutasteride, the dual 5alpha-reductase inhibitor, inhibits androgen action and promotes cell death in the LNCaP prostate cancer cell line. diagnostic usage,ongoing research,therapeutic application,unassigned 1,4,3,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15310997&form=6&db=m Effect of the dual 5alpha-reductase inhibitor dutasteride on markers of tumor regression in prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,3,4,4 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16018939&form=6&db=m Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic hyperplasia and prostate cancer. causal interaction,diagnostic usage,ongoing research,therapeutic application 4,1,4,3 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19215786&form=6&db=m Association among polymorphisms in the steroid 5alpha-reductase type II (SRD5A2) gene, prostate cancer risk, and pathologic characteristics of prostate tumors in an Ecuadorian population. causal interaction,diagnostic usage,unassigned 4,1,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19760631&form=6&db=m SRD5A2 V89L polymorphism and prostate cancer risk: A meta-analysis. diagnostic usage,ongoing research,unassigned 1,2,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23579488&form=6&db=m SULT2B1b sulfotransferase: induction by vitamin D receptor and reduced expression in prostate cancer. causal interaction,diagnostic usage,ongoing research,unassigned 2,4,3,0 1.3.1.22 Prostatic Neoplasms http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=32989395&form=6&db=m Steroid 5 alpha-reductase 2 enzyme variants, biomass exposure and tobacco use in Mexican patients with prostate cancer. causal interaction,diagnostic usage,unassigned 3,2,0 1.3.1.22 Retinal Dystrophies http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=30019980&form=6&db=m Early-onset retinal dystrophy and chronic dermatitis in a girl with an undiagnosed congenital disorder of glycosylation (SRD5A3-CDG). causal interaction,diagnostic usage,therapeutic application,unassigned 3,1,1,0 1.3.1.22 Seminoma http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12576851&form=6&db=m Giant seminoma in a patient with 5 alpha-reductase type 2 deficiency. causal interaction,unassigned 4,0