2.7.7.86	free enzyme or bound to a 16 base pair complementary double stranded DNA and ATP	
2.7.7.86	purified recombinant h-cGASCD in apoform and complexed with inhibitors, by hanging drop vapor diffusion method, mixing of 0.0015 ml of 8-9 mg/ml protein in 20 mM HEPES, pH 7.5, 250 mM KCl, 1 mM TCEP, and 10% glycerine, with 0.0015 ml of reservoir solution containing 17.5-19% v/v PEG 3350 and 0.2 M ammonium citrate, pH 7.0-7.5, 4°C, soaking of crystals for the inhibitor PF-06928215-enzyme complex, X-ray diffraction structure determination and analysis at 1.8 A resolution, molecular replacement using structure PDB ID 4LEV as a search model	
2.7.7.86	sitting drop vapor diffusion method, using 18% (w/v) PEG3350, 0.2 M ammonium nitrate, 0.5 M NaCl, and 0.02 mM CYMAL-7	
2.7.7.86	structure of cGAS catalytic domain	
2.7.7.86	structure of mouse cGAS bound to an 18 bp dsDNA. cGAS interacts with dsDNA through two binding sites, forming a 2:2 complex. enzyme forms a dimer in the crystal