1.14.16.1 (6R)-5,6,7,8-tetrahydro-L-monapterin 7% of the activity with tetrahydrobiopterin 687580 1.14.16.1 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin - 699374, 712471 1.14.16.1 (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin i.e. 6(R)BH4, essential cofactor 673511 1.14.16.1 (7R)-tetrahydrobiopterin 8fold lower affinity and activity compared with 6(R)BH4 673511 1.14.16.1 (7S)-tetrahydrobiopterin 8fold lower affinity and activity compared with 6(R)BH4 673511 1.14.16.1 5,6,7,8-tetrahydro-L-biopterin - 659643, 696226, 697593, 697799, 697830, 699022, 699060, 699235, 699316, 699746, 700231, 701083 1.14.16.1 5,6,7,8-tetrahydro-L-biopterin PAH can be activated up to 20times in the presence of its natural cofactor 5,6,7,8-tetrahydro-L-biopterin but cannot be activated in the presence of synthetic cofactors such as 6,7-dimethyltetrahydrobiopterin or 6-methyltetrahydropterin 700235 1.14.16.1 5,6,7,8-tetrahydrobiopterin - 672057 1.14.16.1 6,7-dimethyl-5,6,7,8-tetrahydrobiopterin - 659519 1.14.16.1 6,7-dimethyltetrahydropterin 17% of the activity with tetrahydrobiopterin 687580