1.1.1.82	NAD+	NADP+ is the preferred cofactor compared to NAD+ with substrate (S)-malate, while NAD+ is preferred with substrate tartrate. Ala at position 53 is responsible for coenzyme specificity, and the next residue, Arg, is important for NADP+ binding, structural analysis and comparison	696461	
1.1.1.82	NADP+	-	739249, 740926, 741200, 762295, 762354	
1.1.1.82	NADP+	NADP+ binds to Ser9, Arg34, His36, Ser37, Ile121, Asn123, and Glu219	740926	
1.1.1.82	NADP+	NADP+ is the preferred cofactor compared to NAD+ with substrate (S)-malate, while NAD+ is preferred with substrate tartrate. Ala at position 53 is responsible for coenzyme specificity, and the next residue, Arg, is important for NADP+ binding, structural analysis and comparison	696461	
1.1.1.82	NADPH	-	739249, 740926, 741200, 762295, 762354	
1.1.1.82	NADPH	cofactor	287384, 287385, 287386, 287387	
1.1.1.82	NADPH	nicotinamide binds to the hydrophobic cleft of MDH from Thermus flavus composed of Leu40, Ile42, Ile107, Thr9, Gly10, Gly87, and Ala88	740926