1.2.1.31 - 1.2.1.31 cDNA is cloned from a human fetal library, library is constructed in a modified pBluescript II SK+ vector, cDNA insert is sequenced 1.2.1.31 cloning of lys2, the cloned gene encodes a functional alpha-aminoadipate reductase as shown by complementation of a Penicillium chrysogenum lys2 mutant, the aminoacid sequence shows strong homology with the alpha-aminoadipate reductase encoded by lys2 genes of Candida albicans, Schizosaccharomyces pombe, Saccharomyces cerevisiae and Penicillium chrysogenum 1.2.1.31 cloning of the LYS2 gene 1.2.1.31 encoded by two different genes, LYS2 and LYS5 1.2.1.31 expression in Escherichia coli as an active enzyme. Exhibits significant alpha-aminoadipate reductase activity without the addition of CoA and Lys7p PPTase from Schizosaccharomyces pombe 1.2.1.31 heterlogous expressed in Escherichia coli 1.2.1.31 LYS2 gene cloned 1.2.1.31 LYS2 gene codes for alpha-aminoadipate reductase, construction and use of LYS2 cartridges 1.2.1.31 LYS2 gene codes for alpha-aminoadipate reductase, LYS2 genes encodes a protein with 49.9% identity to the Saccharomyces cerevisiae, 51.3% identity to the Schizosaccharomyces pombe and 48.12% identity to the Candida albicans alpha-aminoadipate reductases