1.3.1.20 AKR1C1, AKR1C2, DD, DDH, DDH1, DDH2, dehydrogenase, trans-1,2-dihydrobenzene-1,2-diol, DHDH, dihydrodiol dehydrogenase - 1.3.1.20 additional information DD4 shows only 83% sequence homology to the other human DD isoforms 1.3.1.20 DDH member of the aldo-keto reductases superfamily which plays a central role in the metabolism of steroid hormones, prostaglandins and xenobiotics 1.3.1.20 additional information sequence analysis revealed high sequence homology between dimeric mammalian dihydrodiol dehydrogenases, but no homology with monomeric or cis-dihydrodiol-specific enzymes