2.4.2.60	additional information	Thi4 is a suicidal enzyme undergoing only a single turnover	Saccharomyces cerevisiae	?	-	?	89	
2.4.2.60	additional information	mechanism starts with cleavage of the N-glycosyl bond of NAD followed by ring opening, tautomerization and loss of water. Reaction continues with imine formation, tautomerization, sulfide addition and cyclization. Elimination of two water molecules followed by a tautomerization completes the formation of the thiazole moiety	Saccharomyces cerevisiae	?	-	?	89	
2.4.2.60	additional information	mechanism starts with cleavage of the N-glycosyl bond of NAD followed by ring opening, tautomerization and loss of water. Reaction continues with imine formation, tautomerization, sulfide addition and cyclization. Elimination of two water molecules followed by a tautomerization completes the formation of the thiazole moiety	Saccharomyces cerevisiae ATCC 204508	?	-	?	89	
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Saccharomyces cerevisiae	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?	442486	
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Triticum aestivum	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?	442486	
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Hordeum vulgare	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?	442486	
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Arabidopsis thaliana	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?	442486	
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Avena sativa	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?	442486	
2.4.2.60	NAD+ + glycine + [ADP-thiazole synthase]-L-cysteine	-	Caladium bicolor	nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + [ADP-thiazole synthase]-dehydroalanine + 3 H2O	-	?	442486