1.1.3.45	2 aclacinomycin N + O2	the bifunctional enzyme catalyzes the last two steps in the biosynthesis of polyketide antibiotics of the aclacinomycin group, the oxidation of the terminal sugar moiety rhodinose to cinerulose A and the oxidation of cinerulose A to L-aculose	Streptomyces galilaeus	2 aclacinomycin A + H2O2	-	?	421778	
1.1.3.45	2 aclacinomycin N + O2	bifunctional enzyme. The two different reactions of AknOx are catalyzed in the same active site but by different active site residues. Tyr450 is responsible for proton removal from the C4 hydroxyl group in the first reaction, the oxidation of rhodinose to cinerulose A. Tyr378 acts as a catalytic base involved in proton abstraction from C3 of cinerulose A in the second reaction, for formation L-aculose	Streptomyces galilaeus	2 aclacinomycin A + H2O2	-	?	421778