4.1.1.81	L-serine O-3-phosphate	-	ethanolamine-phosphate + CO2	-	?	444353	
4.1.1.81	L-threonine O-3-phosphate	-	(R)-1-aminopropan-2-yl phosphate + CO2	-	?	359177	
4.1.1.81	L-threonine O-3-phosphate	enzyme shows stereospecificity for the L-isomer, unable to decarboxylate the D-isomer	(R)-1-aminopropan-2-yl phosphate + CO2	-	?	359177	
4.1.1.81	L-threonine O-3-phosphate	adenosylcobalamin biosynthesis, end product of the corrin ring biosynthetic pathway is 5'-deoxyadenosylcobinamide phosphate, not 5'-deoxyadenosylcobinamide	(R)-1-aminopropan-2-yl phosphate + CO2	-	?	359177	
4.1.1.81	L-threonine O-3-phosphate	biosynthetic pathway of cobalamin, essential cofactor for many living organisms, only synthesized de novo by bacteria and archaea	(R)-1-aminopropan-2-yl phosphate + CO2	precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin	?	359177	
4.1.1.81	L-threonine O-3-phosphate	de novo synthesis of enzymatic cofactors, cobalamin biosynthetic pathway	(R)-1-aminopropan-2-yl phosphate + CO2	precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin	?	359177	
4.1.1.81	additional information	CobD does not have lactaldehyde aminotransferase activity	?	-	?	89	
4.1.1.81	additional information	bifunctional enzyme with L-threonine-O-3-phosphate decarboxylase (EC 4.1.1.81) and L-Thr kinase activities (EC 2.7.1.177). Using ATP and L-Thr as substrates, the enzyme generates ADP, L-Thr-P, and (R)-1-aminopropan-2-ol O-phosphate as products. No substrate: L-serine phosphate	?	-	?	89