2.9.1.2	L-phosphoseryl-tRNASec + selenophosphate	-	Trypanosoma brucei	L-selenocysteinyl-tRNASec + phosphate	-	?	398919	
2.9.1.2	L-phosphoseryl-tRNASec + selenophosphate	selenocysteine is the only genetically encoded amino acid in humans whose biosynthesis occurs on its cognate transfer RNA (tRNA). O-Phosphoseryl-tRNA:selenocysteinyl-tRNA synthase catalyzes the final step of selenocysteine formation by a tRNA-dependent mechanism	Homo sapiens	L-selenocysteinyl-tRNASec + phosphate	-	?	398919	
2.9.1.2	additional information	bacterial SepCysS charges bacterial tRNACys species with cysteine in vitro. Sep-tRNACys is converted by Sep-tRNA:Cys-tRNA synthase (SepCysS) to Cys-tRNACys	Bacteria	?	-	-	89	
2.9.1.2	additional information	Sep-tRNACys is converted by Sep-tRNA:Cys-tRNA synthase (SepCysS) to Cys-tRNACys	Archaea	?	-	-	89	
2.9.1.2	additional information	SepSecS binds unacylated tRNASec equally well as Sep-tRNASec 1	Homo sapiens	?	-	-	89	
2.9.1.2	O-phospho-L-seryl-tRNASec + selenophosphate	-	Trypanosoma brucei	L-selenocysteinyl-tRNASec + phosphate	-	?	398974	
2.9.1.2	O-phospho-L-seryl-tRNASec + selenophosphate	-	Homo sapiens	L-selenocysteinyl-tRNASec + phosphate	-	?	398974	
2.9.1.2	O-phospho-L-seryl-tRNASec + selenophosphate	-	Methanococcus maripaludis	L-selenocysteinyl-tRNASec + phosphate	-	?	398974	
2.9.1.2	O-phospho-L-seryl-tRNASec + selenophosphate	-	Methanocaldococcus jannaschii	L-selenocysteinyl-tRNASec + phosphate	-	?	398974	
2.9.1.2	O-phospho-L-seryl-tRNASec + selenophosphate	L-phosphoseryl-tRNA is the crucial precursor for L-selenocysteinyl-tRNA formation in archaea and eukarya. Selenocysteine formation is achieved by a two-step process: O-phosphoseryl-tRNASec kinase (PSTK) phosphorylates the endogenous Ser-tRNASec to O-phosphoseryl-tRNASec, and then this misacylated amino acid-tRNA species is converted to L-selenocysteinyl-tRNASec by Sep-tRNA:Sec-tRNA synthase (SepSecS)	Methanococcus maripaludis	L-selenocysteinyl-tRNASec + phosphate	-	?	398974