2.1.1.284 S-adenosyl-L-methionine + 8-demethylnovobiocic acid - Streptomyces niveus S-adenosyl-L-homocysteine + novobiocic acid - ? 422046 2.1.1.284 S-adenosyl-L-methionine + 8-demethylnovobiocic acid the enzyme is involved in the biosynthesis of the aminocoumarin antibiotic, novobiocin Streptomyces niveus S-adenosyl-L-homocysteine + novobiocic acid - ? 422046