3.6.1.25	ATP + H2O	low affinity	Nitrosomonas europaea	?	-	64622	
3.6.1.25	additional information	the enzyme has low affinity for CTP, ATP or thiamine triphosphate. Nucleoside triphosphatase activity is negligible in the presence of 5 mM Mg2+, but a small activity is observed in the presence of 1 mM Mn2+, in particular with GTP. Guanosine 5’-tetraphosphate and long chain polyphosphate (containing about 65 phosphate residues) are not hydrolyzed. The enzyme has no adenylyl cyclase activity	Nitrosomonas europaea	?	-	89	
3.6.1.25	triphosphate + H2O	-	Rattus norvegicus	diphosphate + phosphate	-	73542	
3.6.1.25	triphosphate + H2O	-	Neurospora crassa	diphosphate + phosphate	-	73542	
3.6.1.25	triphosphate + H2O	-	Vaccinia virus	diphosphate + phosphate	-	73542	
3.6.1.25	triphosphate + H2O	-	Kitasatospora aureofaciens	diphosphate + phosphate	-	73542	
3.6.1.25	triphosphate + H2O	involved in phosphorous and energy exchange of mitochondria	Neurospora crassa	diphosphate + phosphate	-	73542	
3.6.1.25	triphosphate + H2O	involved in transcription termination	Vaccinia virus	diphosphate + phosphate	-	73542	
3.6.1.25	tripolyphosphate + H2O	very good substrate with Mg2+ as activator. The enzyme has a strong preference for linear tripolyphosphate compared with cyclic trimetaphosphate and to the linear tetraphosphate	Nitrosomonas europaea	diphosphate + phosphate	-	141219