3.2.1.76 2,5-anhydro-3-O-alpha-L-idopyranuronosyl-D-mannitol + H2O - Homo sapiens ? - ? 115791 3.2.1.76 2,5-anhydro-4-O-alpha-L-idopyranuronosyl-D-mannitol 6-sulfate + H2O - Homo sapiens ? - ? 115790 3.2.1.76 4-methylcoumarin-7-yl-alpha-L-iduronic acid + H2O design and development of an improved and less expensive synthesis method for the fluorogenic substrate, overview. The method is based on the double ketal fixation of the 1,2 and 3,5-hydroxy groups of D-glucose to form a cis-anti-cis-fused tricyclic D-glucofuranosyl derivative, which could undergo elimination to form a 5-exo-double bond followed by electrophilic addition, a Mitsunobu-type glycosylation reaction is used for the coupling of the hemiacetal with the acceptor Homo sapiens 4-methylcoumarin + alpha-L-iduronic acid - ? 431365 3.2.1.76 4-methylumbelliferyl alpha-L-iduronide + H2O - Homo sapiens 4-methylumbelliferone + alpha-L-iduronic acid - ? 446062 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Homo sapiens ? - ? 115789 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Rattus norvegicus ? - ? 115789 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Sus scrofa ? - ? 115789 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Bos taurus ? - ? 115789 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Mus musculus 4-methylumbelliferone + alpha-L-iduronic acid - ? 372008 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Homo sapiens 4-methylumbelliferone + alpha-L-iduronic acid - ? 372008 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Mus musculus 4-methylumbelliferol + alpha-L-iduronic acid - ? 431378 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Homo sapiens 4-methylumbelliferol + alpha-L-iduronic acid - ? 431378 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + H2O - Mus musculus C57BL/6 4-methylumbelliferol + alpha-L-iduronic acid - ? 431378 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronide + methanol methanolysis Homo sapiens ? - ? 372009 3.2.1.76 4-methylumbelliferyl-alpha-L-iduronoside + H2O - Homo sapiens 4-methylumbelliferone + alpha-L-iduronic acid - ? 411324 3.2.1.76 4-nitrophenyl-alpha-L-idopyranosiduronate + H2O - Homo sapiens 4-nitrophenol + alpha-L-iduronic acid - ? 372070 3.2.1.76 4-nitrophenyl-alpha-L-iduronide + H2O - Homo sapiens 4-nitrophenol + alpha-L-iduronic acid - ? 381204 3.2.1.76 5-fluoro-alpha-L-idopyranosyluronic acid fluoride + H2O - Homo sapiens fluoride + ? - ? 372130 3.2.1.76 alpha-L-iduronosyl(1-4)anhydromannitol-6-sulfate + H2O - Homo sapiens ? - ? 381398 3.2.1.76 alpha-L-iduronosyl-(1->3)-2,5-anhydro-D-talitol 4-sulfate + H2O - Homo sapiens ? - ? 115787 3.2.1.76 alpha-L-iduronysyl-(alpha-1,4)2,5-anhydro-D-mannitol-6-sulfate + H2O - Homo sapiens 2,5-anhydro-D-mannitol 6-sulfate + alpha-L-iduronic acid - ? 372350 3.2.1.76 anhydromannitol iduronide + H2O - Homo sapiens ? - ? 115786 3.2.1.76 dermatan sulfate + H2O - Homo sapiens ? + alpha-iduronic acid - ? 430959 3.2.1.76 glycosaminoglycan + H2O - Homo sapiens ? + alpha-iduronic acid - ? 431004 3.2.1.76 heparan sulfate + H2O - Homo sapiens ? + alpha-L-iduronic acid - ? 430999 3.2.1.76 IdoA-GlcNAc6S-IdoA2S-anM6S + H2O O-(alpha-L-iduronic acid)-(1,4)-D-O-(alpha-N-acetylglucosamine 6-sulphate)-L-O-(alpha-iduronic acid 2-sulphate)-O-D-2,5-anhydro-D-mannitol 6-sulphate Homo sapiens ? - ? 115792 3.2.1.76 IdoA-GlcNH6S-IdoA2S-anM6S + H2O - Homo sapiens ? - ? 452828 3.2.1.76 IdoA-GlcNS6S-IdoA2S-anM6S + H2O - Homo sapiens ? - ? 452829 3.2.1.76 additional information cleaves alpha-L-iduronic acid from the nonreducing ends of dermatan sulfate, heparin, and heparan sulfate, deficiency in alpha-L-iduronidase causes mucopolysaccharidosis type I Homo sapiens ? - ? 89 3.2.1.76 additional information involved in the degradation of dermatan sulfate and heparan sulfate Homo sapiens ? - ? 89 3.2.1.76 additional information involved in the degradation of dermatan sulfate and heparan sulfate, deficiency in alpha-L-iduronidase causes mucopolysaccharidosis type I Homo sapiens ? - ? 89 3.2.1.76 additional information enzyme deficiency causes mucopolysaccharidosis type I, MPSI Homo sapiens ? - ? 89 3.2.1.76 additional information enzyme deficiency causes the lysosomal storage disorder mucopolysaccharidosis type I, MPSI Homo sapiens ? - ? 89 3.2.1.76 additional information the enzyme is involved in mucopolysaccharidosis type I Homo sapiens ? - ? 89 3.2.1.76 additional information the enzyme is involved in the sequential degradation of heparan sufate and dermatan sulfate, enzyme deficiency results in the accumulation and urinary secretion of partially degraded glycosaminoglycans and causes the lysosomal storage disorder mucopolysaccharidosis type I, MPSI Homo sapiens ? - ? 89 3.2.1.76 additional information substrate specificity of recombinant enzyme with and without a C-terminal ER-retention signal from seeds of Brassica napus and Nicotiana tabacum, overview Homo sapiens ? - ? 89 3.2.1.76 additional information the enzyme cleaves terminal alpha-iduronic acid residues from glycosaminoglycan, heparan sulfate and dermatan sulfate Homo sapiens ? - ? 89 3.2.1.76 additional information the enzyme hydrolyses the glycosidic bond between the terminal L-iduronic acid and the second sugar of N-acetylgalactosamine-4-sulfate/N-sulfo-D-glucosamine-6-sulfate, which are the major components of dermatan/heparan sulfate Homo sapiens ? - ? 89 3.2.1.76 additional information the enzyme hydrolyzes terminal iduronic acid residues on glycosaminoglycans Homo sapiens ? - ? 89 3.2.1.76 phenyl alpha-L-iduronide + H2O - Homo sapiens ? - ? 115785 3.2.1.76 phenyl alpha-L-iduronide + H2O - Rattus norvegicus ? - ? 115785