2.5.1.104	additional information	only faint activities (less than 10% of spermidine) are detected for diaminopropane [NH2(CH2)3NH2], putrescine, spermine, and caldopentamine	Thermus thermophilus	?	-	?	89	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	the enzyme is involved in polyamine biosynthesis	Thermococcus kodakarensis	5'-S-methyl-5'-thioadenosine + N1-aminopropylagamatine	-	?	419552	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	-	Thermococcus kodakarensis	5'-S-methyl-5'-thioadenosine + N1-aminopropylagmatine	-	?	419553	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	-	Thermus thermophilus	5'-S-methyl-5'-thioadenosine + N1-aminopropylagmatine	-	?	419553	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	the enzyme is involved in polyamine biosynthesis	Thermus thermophilus	5'-S-methyl-5'-thioadenosine + N1-aminopropylagmatine	-	?	419553	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	agmatine is the physiological substrate in the constitutive synthesis of spermidine, while cadaverine acts as an aminopropyl acceptor under stress conditions when an active and rapid synthesis of N-(3-aminopropyl)cadaverine could be required	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + N1-aminopropylagmatine	-	?	419553	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	4.9% of the activity compared to cadaverine	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + N1-aminopropylagmatine	-	?	419553	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + agmatine	-	Thermus thermophilus	S-methyl-5'-thioadenosine + N1-aminopropylagmatine	-	?	421297	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + cadaverine	-	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + N-(3-aminopropyl)cadaverine	-	?	419554	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + cadaverine	-	Thermococcus kodakarensis	5'-S-methyl-5'-thioadenosine + N-(3-aminopropyl)cadaverine	-	?	419554	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + cadaverine	agmatine is the physiological substrate in the constitutive synthesis of spermidine, while cadaverine acts as an aminopropyl acceptor under stress conditions when an active and rapid synthesis of N-(3-aminopropyl)cadaverine could be required	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + N-(3-aminopropyl)cadaverine	-	?	419554	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + homospermidine	low activity	Thermus thermophilus	S-methyl-5'-thioadenosine + ?	-	?	421299	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + N,N'-bis(3-aminopropyl)-1,3-propanediamine	i.e. thermine. Low activity	Thermus thermophilus	S-methyl-5'-thioadenosine + ?	-	?	421300	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + norspermidine	-	Thermus thermophilus	S-methyl-5'-thioadenosine + N,N'-bis(3-aminopropyl)-1,3-propanediamine	i.e. thermine	?	421301	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + propane-1,3-diamine	2.9% of the activity compared to cadaverine	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine	-	?	421302	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + putrescine	-	Thermococcus kodakarensis	5'-S-methyl-5'-thioadenosine + spermidine	-	?	421303	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + putrescine	8.7% of the activity compared to cadaverine	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + spermidine	-	?	421303	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + spermidine	0.8% of the activity compared to cadaverine	Pyrococcus furiosus	5'-S-methyl-5'-thioadenosine + spermine	-	?	421305	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + spermidine	-	Thermus thermophilus	S-methyl-5'-thioadenosine + spermine	no formation of thermospermine (i.e. 1,12-diamino-4,8-diazadodecane)	?	421306	
2.5.1.104	S-adenosyl 3-(methylthio)propylamine + tris(3-aminopropyl)amine	i.e. mitsubishine. Low activity. No formation of tetrakis(3-aminopropyl)ammonium	Thermus thermophilus	S-methyl-5'-thioadenosine + N4-aminopropylthermine	-	?	421307