2.2.1.5	2-oxoglutarate	-	Mycolicibacterium phlei	? + CO2	-	?	260890	
2.2.1.5	2-oxoglutarate	decarboxylation	Bos taurus	? + CO2	-	?	260890	
2.2.1.5	2-oxoglutarate	identical with 2-oxoglutarate decarboxylase	Tetrahymena pyriformis	? + CO2	-	?	260890	
2.2.1.5	2-oxoglutarate + acetaldehyde	-	Saccharomyces cerevisiae	5-hydroxy-4-oxohexanoate + CO2	-	?	260889	
2.2.1.5	2-oxoglutarate + acetaldehyde	-	Bos taurus	5-hydroxy-4-oxohexanoate + CO2	-	?	260889	
2.2.1.5	2-oxoglutarate + acetaldehyde	-	Mycolicibacterium phlei	5-hydroxy-4-oxohexanoate + CO2	-	?	260889	
2.2.1.5	2-oxoglutarate + ethyl glyoxylate	-	Escherichia coli	(R)-6-ethoxy-5-hydroxy-4,6-dioxohexanoic acid + CO2	81% enantiomeric excess	?	435045	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Nicotiana rustica	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Escherichia coli	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Rattus norvegicus	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Sus scrofa	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Saccharomyces cerevisiae	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Oryctolagus cuniculus	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Tetrahymena pyriformis	2-hydroxy-3-oxohexandioate + CO2	-	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Bos taurus	2-hydroxy-3-oxohexandioate + CO2	i. e. 2-hydroxy-3-oxoadipic acid	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Tetrahymena pyriformis	2-hydroxy-3-oxohexandioate + CO2	i. e. 2-hydroxy-3-oxoadipic acid	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Bos taurus	2-hydroxy-3-oxohexandioate + CO2	also 2,3-dihydroxy-4-ketopimelic acid	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Tetrahymena pyriformis	2-hydroxy-3-oxohexandioate + CO2	further spontaneous decarboxylation in the presence of acid	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Mycolicibacterium phlei	2-hydroxy-3-oxohexandioate + CO2	further spontaneous decarboxylation in the presence of acid	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Bos taurus	2-hydroxy-3-oxohexandioate + CO2	further decarboxylation leads to 5-hydroxy-4-ketovaleric acid	?	260888	
2.2.1.5	2-oxoglutarate + glyoxylate	linked to citric acid cycle	Rattus norvegicus	?	-	?	370219	
2.2.1.5	2-oxoglutarate + glyoxylate	linked to citric acid cycle	Oryctolagus cuniculus	?	-	?	370219	
2.2.1.5	2-oxoglutarate + glyoxylate	possible 1-carbon source for nicotine synthesis	Nicotiana rustica	?	-	?	370219	
2.2.1.5	2-oxoglutarate + glyoxylate	hypothesized 2-oxoglutarate regeneration cycle	Tetrahymena pyriformis	?	-	?	370219	
2.2.1.5	2-oxoglutarate + glyoxylate	important as diversion of glyoxylate from oxalate formation	Rattus norvegicus	?	-	?	370219	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Bos taurus	2-hydroxy-3-oxoadipate + CO2	-	?	375703	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Mycobacterium tuberculosis	2-hydroxy-3-oxoadipate + CO2	-	?	375703	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Mycobacterium tuberculosis CDC1551	2-hydroxy-3-oxoadipate + CO2	-	?	375703	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Mycobacterium tuberculosis H37Rv	2-hydroxy-3-oxoadipate + CO2	-	?	375703	
2.2.1.5	2-oxoglutarate + glyoxylate	-	Escherichia coli	(R)-2-hydroxy-3-oxoadipate + CO2	90% enantiomeric excess	?	435046	
2.2.1.5	2-oxoglutarate + methylglyoxal	-	Escherichia coli	(R)-5-hydroxy-4,6-dioxoheptanoic acid + CO2	83% enantiomeric excess	?	435047	
2.2.1.5	2-oxoisovalerate + ethyl glyoxylate	-	Escherichia coli	(S)-ethyl 2-hydroxy-4-methyl-3-oxopentanoic acid + CO2	81% enantiomeric excess	?	435050	
2.2.1.5	2-oxoisovalerate + glyoxylate	-	Escherichia coli	(S)-2-hydroxy-4-methyl-3-oxopentanoic acid + CO2	67% enantiomeric excess	?	435051	
2.2.1.5	2-oxoisovalerate + methylglyoxal	-	Escherichia coli	(S)-3-hydroxy-5-methylhexane-2,4-dione + CO2	more than 90% enantiomeric excess	?	435052	
2.2.1.5	2-oxovalerate + ethyl glyoxylate	-	Escherichia coli	(S)-ethyl 2-hydroxy-3-oxohexanoic acid + CO2	52% enantiomeric excess	?	435059	
2.2.1.5	2-oxovalerate + glyoxylate	-	Escherichia coli	(S)-2-hydroxy-3-oxohexanoic acid + CO2	96% enantiomeric excess	?	435060	
2.2.1.5	2-oxovalerate + methylglyoxal	-	Escherichia coli	(S)-3-hydroxyheptane-2,4-dione + CO2	81% enantiomeric excess	?	435061	
2.2.1.5	additional information	catalyzing C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of a second substrate, glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA)	Mycobacterium tuberculosis	?	-	?	89	
2.2.1.5	additional information	Rv1248c catalyzes C-C bond formation between the activated aldehyde of alpha-ketoglutarate and the carbonyl of glyoxylate to yield 2-hydroxy-3-oxoadipate (HOA), which decomposes to 5-hydroxylevulinate	Mycobacterium tuberculosis	?	-	?	89	
2.2.1.5	additional information	enzyme catalyzes consumption of 2-oxoglutarate in a mycobacterial small molecule extract with matched production of 5-hydroxylevulinate (HLA) in a reaction predicted to require glyoxylate	Mycobacterium tuberculosis	?	-	?	89	
2.2.1.5	additional information	catalyzing C-C bond formation between the activated aldehyde formed after decarboxylation of alpha-ketoglutarate and the carbonyl of a second substrate, glyoxylate (GLX), to yield 2-hydroxy-3-oxoadipate (HOA)	Mycobacterium tuberculosis H37Rv	?	-	?	89	
2.2.1.5	additional information	Rv1248c catalyzes C-C bond formation between the activated aldehyde of alpha-ketoglutarate and the carbonyl of glyoxylate to yield 2-hydroxy-3-oxoadipate (HOA), which decomposes to 5-hydroxylevulinate	Mycobacterium tuberculosis H37Rv	?	-	?	89	
2.2.1.5	additional information	enzyme catalyzes consumption of 2-oxoglutarate in a mycobacterial small molecule extract with matched production of 5-hydroxylevulinate (HLA) in a reaction predicted to require glyoxylate	Mycobacterium tuberculosis H37Rv	?	-	?	89