2.1.1.155	additional information	the role of F 4’-OMT is mainly defensive against parasites, rather than structural	Dianthus caryophyllus	?	-	?	89	
2.1.1.155	additional information	not: 4-hydroxybenzoic acid, gallic acid, p-coumaric acid, caffeic acid, caffeoyl-CoA, quercetin, rutin, luteolin, eriodictyol, 3’,4’,7’-trihydroxyisoflavone, datiscetin	Dianthus caryophyllus	?	-	?	89	
2.1.1.155	additional information	not: naringenin, pentahydroxyflavanone, hesperetin, myricetin, 7,3’-O-dimethylquercetin, 7-O-methylquercetin, syringetin, apigenin, luteolin, tricetin, velutin, dihydrokaempferol, dihydroquercetin, dihydromyricetin, 3’-O-methyl-dihydroquercetin	Catharanthus roseus	?	-	?	89	
2.1.1.155	S-adenosyl-L-methionine + 4'-hydroxyflavanone	-	Dianthus caryophyllus	S-adenosyl-L-homocysteine + 4'-methoxyflavanone	-	?	374592	
2.1.1.155	S-adenosyl-L-methionine + a flavonoid	4’-OMT methylates the position 4’ in the B-ring of flavonoids, uses flavonoids methylated in the 3’-position of the B-ring to synthesize a 3’,4’-methylated product, a methylated flavanone, homoeriodictyol, is the best substrate	Catharanthus roseus	S-adenosyl-L-homocysteine + a 4'-methoxyflavonoid	-	?	374593	
2.1.1.155	S-adenosyl-L-methionine + a flavonoid	F 4’-OMT specifically methylates the hydroxy substituent in 4’-position of the flavones, flavanones and isoflavones in the presence of S-adenosyl-L-methionine, enzyme affinity for the substrate and catalytic efficiency decreases in the following order: 4’-hydroxyflavones, 4’-hydroxyflavanones, 4’-hydroxyisoflavones, ping-pong mechanism, which excludes the formation of a ternary complex	Dianthus caryophyllus	S-adenosyl-L-homocysteine + a 4'-methoxyflavonoid	-	?	374593	
2.1.1.155	S-adenosyl-L-methionine + apigenin	-	Dianthus caryophyllus	S-adenosyl-L-homocysteine + acacetin	4’-methoxyapigenin	?	374595	
2.1.1.155	S-adenosyl-L-methionine + chrysoeriol	good substrate	Catharanthus roseus	S-adenosyl-L-homocysteine + 4'-methoxychrysoeriol	-	?	374596	
2.1.1.155	S-adenosyl-L-methionine + eriodictyol	lower activity than with homoeriodictyol, isorhamnetin or chrysoeriol	Catharanthus roseus	S-adenosyl-L-homocysteine + 4'-methoxyeriodictyol	-	?	374597	
2.1.1.155	S-adenosyl-L-methionine + genistein	-	Dianthus caryophyllus	S-adenosyl-L-homocysteine + biochanin A	4’-methoxygenistein	?	289635	
2.1.1.155	S-adenosyl-L-methionine + homoeriodictyol	best substrate	Catharanthus roseus	S-adenosyl-L-homocysteine + 4'-methoxyhomoeriodictyol	-	?	374598	
2.1.1.155	S-adenosyl-L-methionine + isorhamnetin	good substrate	Catharanthus roseus	S-adenosyl-L-homocysteine + 4'-methoxyisorhamnetin	-	?	374599	
2.1.1.155	S-adenosyl-L-methionine + kaempferol	-	Dianthus caryophyllus	S-adenosyl-L-homocysteine + kaempferide	-	?	374601	
2.1.1.155	S-adenosyl-L-methionine + kaempferol	lower activity than with homoeriodictyol, isorhamnetin or chrysoeriol	Catharanthus roseus	S-adenosyl-L-homocysteine + kaempferide	-	?	374601	
2.1.1.155	S-adenosyl-L-methionine + kaempferol 3-O-beta-D-glucopyranosyl-1,4-O-alpha-L-rhamnopyranosyl-1,2-beta-D-glucopyranoside	-	Dianthus caryophyllus	S-adenosyl-L-homocysteine + 4'-O-methylkaempferol 3-O-beta-D-glucopyranosyl-1,4-O-alpha-L-rhamnopyranosyl-1,2-beta-D-glucopyranoside	-	?	374600	
2.1.1.155	S-adenosyl-L-methionine + quercetin	lower activity than with homoeriodictyol, isorhamnetin or chrysoeriol	Catharanthus roseus	S-adenosyl-L-homocysteine + 4'-methoxyquercetin	-	?	374602