1.1.1.72 (2,2-dimethyl-1,3-dioxolan-4-yl)methanol + NADP+ oxidation reaction. Specific activity: 0.03 micromol/min/mg Gluconobacter oxydans 2,2-dimethyl-1,3-dioxolane-4-carbaldehyde + NADPH - ? 413674 1.1.1.72 (2E)-pent-2-enal + NADPH + H+ reduction reaction: specific activity: 4.9 micromol/min/mg. Oxidation reaction specific activity: 0.74 micromol/min/mg Gluconobacter oxydans (2E)-pent-2-enol + NADP+ - ? 413677 1.1.1.72 (2R)-2,4-dihydroxybutanal + NADPH + H+ reduction reaction. Specific activity: 46.6 micromol/min/mg Gluconobacter oxydans (2R)-2,4-dihydroxybutanol + NADP+ - ? 413691 1.1.1.72 (2R,3S)-butane-1,2,3,4-tetrol + NADP+ oxidation reaction. Specific activity: 0.75 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 413693 1.1.1.72 (2R,3S,4R,5S)-hexane-1,2,3,4,5,6-hexol + NADP+ oxidation reaction. Specific activity: 1.08 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 413694 1.1.1.72 (2R,3S,4S)-pentane-1,2,3,4,5-pentol + NADP+ oxidation reaction. Specific activity: 0.25 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 413695 1.1.1.72 (2R,4S)-pentane-1,2,3,4,5-pentol + NADP+ oxidation reaction. Specific activity: 2.46 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 413696 1.1.1.72 (2S)-2,4-dihydroxybutanal + NADPH + H+ reduction reaction. Specific activity: 2.0 micromol/min/mg Gluconobacter oxydans (2S)-2,4-dihydroxybutanol + NADP+ - ? 413698 1.1.1.72 (2S,3S)-butane-1,2,3,4-tetrol + NADP+ oxidation reaction. Specific activity: 0.9 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 413703 1.1.1.72 1,3-dihydroxypropan-2-one + NADPH + H+ reduction reaction. Specific activity: 0.5 micromol/min/mg Gluconobacter oxydans propane-1,2,3-triol + NADP+ - ? 413787 1.1.1.72 1-phenylethane-1,2-diol + NADP+ oxidation reaction. Specific activity: 0.77 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 413837 1.1.1.72 1-phenylethanone + NADPH + H+ reduction reaction. Specific activity: 0.04 micromol/min/mg Gluconobacter oxydans 1-phenylethanol + NADP+ - ? 413838 1.1.1.72 1-phenylpropanone + NADPH + H+ reduction reaction. Specific activity: 0.03 micromol/min/mg Gluconobacter oxydans 1-phenylpropanol + NADP+ - ? 413839 1.1.1.72 2,3-butanedione + NADPH - Aspergillus nidulans ? - ? 188609 1.1.1.72 2,3-butanedione + NADPH - Aspergillus niger ? - ? 188609 1.1.1.72 2,4-difluorobenzaldehyde + NADPH + H+ reduction reaction. Specific activity: 19.6 micromol/min/mg Gluconobacter oxydans (2,4-difluorophenyl)methanol + NADP+ - ? 413891 1.1.1.72 2,4-dihydroxybutanal + NADPH + H+ reduction reaction. Specific activity: 39.1 micromol/min/mg Gluconobacter oxydans 2,4-dihydroxybutanol + NADP+ - ? 413892 1.1.1.72 2-butenal + NADPH - Oryctolagus cuniculus 2-buten-1-ol + NADP+ - ? 188604 1.1.1.72 2-methylbutanal + NADPH + H+ reduction reaction. Specific activity: 26.8 micromol/min/mg Gluconobacter oxydans 2-methylbutanol + NADP+ - ? 413955 1.1.1.72 2-methylpentanal + NADPH + H+ reduction reaction. Specific activity: 25.7 micromol/min/mg Gluconobacter oxydans 2-methylpentanol + NADP+ - ? 413960 1.1.1.72 2-methylpropanal + NADPH + H+ reduction reaction. Specific activity: 6.7 micromol/min/mg Gluconobacter oxydans 2-methylpropanol + NADP+ - ? 413961 1.1.1.72 3-methylbutanal + NADPH - Oryctolagus cuniculus 3-methylbutanol + NADP+ - ? 187615 1.1.1.72 4-methoxybenzaldehyde + NADPH + H+ reduction reaction. Specific activity: 0.3 micromol/min/mg Gluconobacter oxydans (4-methoxyphenyl)methanol + NADP+ - ? 414114 1.1.1.72 4-nitrobenzaldehyde + NADPH - Oryctolagus cuniculus 4-nitrobenzylalcohol + NADP+ - ? 187834 1.1.1.72 6-methylheptane-2,5-dione + NADPH + H+ reduction reaction. Specific activity: 0.03 micromol/min/mg Gluconobacter oxydans ? + NADP+ - ? 414168 1.1.1.72 acetaldehyde + NADPH + H+ - Oryctolagus cuniculus ethanol + NADP+ - ? 139551 1.1.1.72 acetaldehyde + NADPH + H+ reduction reaction. Specific activity: 0.1 micromol/min/mg Gluconobacter oxydans ethanol + NADP+ - ? 139551 1.1.1.72 benzaldehyde + NADPH + H+ reduction reaction. Specific activity: 13.8 micromol/min/mg Gluconobacter oxydans benzyl alcohol + NADP+ - ? 372517 1.1.1.72 benzaldehyde + NADPH + H+ - Gluconobacter oxydans benzylalkohol + NADP+ - ? 414337 1.1.1.72 butanal + NADPH + H+ - Gluconobacter oxydans butanol + NADP+ - ? 404566 1.1.1.72 butanal + NADPH + H+ reduction reaction. Specific activity: 23.3 micromol/min/mg Gluconobacter oxydans butanol + NADP+ - ? 404566 1.1.1.72 butane-1,2,4-triol + NADP+ oxidation reaction. Specific activity: 1.21 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414393 1.1.1.72 butane-1,2-diol + NADP+ oxidation reaction. Specific activity: 0.66 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414394 1.1.1.72 butane-1,3-diol + NADP+ oxidation reaction. Specific activity: 0.04 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414395 1.1.1.72 butane-1,4-diol + NADP+ oxidation reaction. Specific activity: 0.21 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414396 1.1.1.72 D-erythrose + NADPH - Oryctolagus cuniculus erythritol + NADP+ - ? 188601 1.1.1.72 D-glucose + NADPH - Oryctolagus cuniculus sorbitol + NADP+ - ? 188612 1.1.1.72 D-glucuronate + NADP+ - Oryctolagus cuniculus ? - ? 188614 1.1.1.72 D-glyceraldehyde + NADPH + H+ - Rattus norvegicus glycerol + NADP+ - r 187464 1.1.1.72 D-glyceraldehyde + NADPH + H+ - Oryctolagus cuniculus glycerol + NADP+ - r 187464 1.1.1.72 D-glyceraldehyde + NADPH + H+ - Neurospora crassa glycerol + NADP+ - r 187464 1.1.1.72 D-glyceraldehyde + NADPH + H+ - Gluconobacter oxydans glycerol + NADP+ - ? 187464 1.1.1.72 D-glyceraldehyde + NADPH + H+ - Fusarium oxysporum glycerol + NADP+ - r 187464 1.1.1.72 D-glyceraldehyde + NADPH + H+ enzyme favors reduction reaction Gluconobacter oxydans glycerol + NADP+ - ? 187464 1.1.1.72 D-xylose + NADPH - Oryctolagus cuniculus xylitol + NADP+ - ? 188611 1.1.1.72 diacetyl + NADPH - Aspergillus nidulans ? - ? 187325 1.1.1.72 diacetyl + NADPH - Aspergillus niger ? - ? 187325 1.1.1.72 dihydroxyacetone + NADPH - Rattus norvegicus glycerol + NADP+ - r 188602 1.1.1.72 dihydroxyacetone + NADPH - Oryctolagus cuniculus glycerol + NADP+ - r 188602 1.1.1.72 dihydroxyacetone + NADPH - Aspergillus nidulans glycerol + NADP+ - r 188602 1.1.1.72 dihydroxyacetone + NADPH - Aspergillus niger glycerol + NADP+ - r 188602 1.1.1.72 dihydroxyacetone + NADPH - Fusarium oxysporum glycerol + NADP+ - r 188602 1.1.1.72 dihydroxyacetone + NADPH 43% of D-glyceraldehyde activity Neurospora crassa glycerol + NADP+ - r 188602 1.1.1.72 DL-glyceraldehyde + NADPH + H+ significant enantioselectivity Gluconobacter oxydans glycerol + NADP+ - r 383130 1.1.1.72 dodecanal + NADPH + H+ reduction reaction. Specific activity: 19.3 micromol/min/mg Gluconobacter oxydans dodecanol + NADP+ - ? 414579 1.1.1.72 erythritol + NADP+ - Aspergillus nidulans ? - ? 188610 1.1.1.72 erythritol + NADP+ - Aspergillus niger ? - ? 188610 1.1.1.72 ethane-1,1-diol + NADP+ oxidation reaction. Specific activity: 0.5 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414599 1.1.1.72 formaldehyde + NADPH - Rattus norvegicus methanol + NADP+ - ? 139550 1.1.1.72 formaldehyde + NADPH - Oryctolagus cuniculus methanol + NADP+ - ? 139550 1.1.1.72 glycerol + NADP+ - Aspergillus nidulans dihydroxyacetone + NADPH + H+ - r 187357 1.1.1.72 glycerol + NADP+ The enzyme plays a role in the glycerol biosynthesis during growth and in osmotolerance. The glycerol biosynthesis by enzyme is required for germination at high osmolarity. Aspergillus nidulans dihydroxyacetone + NADPH + H+ - r 187357 1.1.1.72 glycerol + NADP+ oxidation reaction. Specific activity: 0.17 micromol/min/mg Gluconobacter oxydans ? + NADPH + H+ - ? 376895 1.1.1.72 glycerol + NADP+ - Lactiplantibacillus plantarum D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ - Lactobacillus delbrueckii D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ - Lactobacillus acidophilus D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ - Gluconobacter oxydans D-glyceraldehyde + NADPH + H+ significant enantioselectivity r 414662 1.1.1.72 glycerol + NADP+ the reverse reaction is energetically more favorable Lactiplantibacillus plantarum D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ the reverse reaction is energetically more favorable Lactobacillus delbrueckii D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ the reverse reaction is energetically more favorable Lactobacillus acidophilus D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ - Lactiplantibacillus plantarum ATCC 8014 D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ the reverse reaction is energetically more favorable Lactiplantibacillus plantarum ATCC 8014 D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ - Lactobacillus delbrueckii UFV-H2B20 D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ the reverse reaction is energetically more favorable Lactobacillus delbrueckii UFV-H2B20 D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ - Lactobacillus acidophilus ATCC 4356 D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycerol + NADP+ the reverse reaction is energetically more favorable Lactobacillus acidophilus ATCC 4356 D-glyceraldehyde + NADPH + H+ - r 414662 1.1.1.72 glycolaldehyde + NADPH - Oryctolagus cuniculus ethyleneglycol + NADP+ - ? 188595 1.1.1.72 glycolaldehyde + NADPH - Neurospora crassa ethyleneglycol + NADP+ - ? 188595 1.1.1.72 hexan-2-ol + NADP+ oxidation reaction. Specific activity: 0.22 micromol/min/mg Gluconobacter oxydans hexan-2-one + NADPH - ? 414696 1.1.1.72 hexanal + NADPH + H+ - Gluconobacter oxydans hexanol + NADP+ - ? 165073 1.1.1.72 hexanal + NADPH + H+ reduction reaction. Specific activity: 31.9 micromol/min/mg Gluconobacter oxydans hexanol + NADP+ - r 165073 1.1.1.72 hexane-1,2,3-triol + NADP+ oxidation reaction. Specific activity: 0.76 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414699 1.1.1.72 hexane-1,2,6-triol + NADP+ oxidation reaction. Specific activity: 0.3 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414700 1.1.1.72 hexane-1,2,6-triol + NADP+ oxidation reaction. Specific activity: 0.45 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414700 1.1.1.72 hexane-1,6-diol + NADP+ oxidation reaction. Specific activity: 0.87 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414701 1.1.1.72 isobutyraldehyde + NADPH + H+ - Oryctolagus cuniculus isobutanol + NADP+ - ? 187768 1.1.1.72 L-arabitol + NADP+ oxidation reaction Gluconobacter oxydans ? + NADPH - ? 187356 1.1.1.72 L-glyceraldehyde + NADPH - Oryctolagus cuniculus glycerol + NADP+ - ? 187558 1.1.1.72 L-glyceraldehyde + NADPH 36% of D-glyceraldehyde activity Neurospora crassa glycerol + NADP+ - ? 187558 1.1.1.72 methanediol + NADP+ oxidation reaction. Specific activity: 0.05 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 414846 1.1.1.72 methylglyoxal + NADPH - Oryctolagus cuniculus 1-hydroxyacetone + NADP+ - ? 188596 1.1.1.72 methylglyoxal + NADPH - Aspergillus nidulans 1-hydroxyacetone + NADP+ - ? 188596 1.1.1.72 methylglyoxal + NADPH - Aspergillus niger 1-hydroxyacetone + NADP+ - ? 188596 1.1.1.72 additional information no substrates: D-fructose, D-ribose, D-xylose Neurospora crassa ? - ? 89 1.1.1.72 additional information the enzyme is part of the biosynthetic pathway for glycerol Aspergillus oryzae ? - ? 89 1.1.1.72 additional information glycerol dehydrogenase activity is detected in all Lactobacillus strains studied but only for the reduction of glyceraldehyde with NADPH. This enzyme shows a very low oxidative activity with glycerol and NADP+ and, most likely, under physiological conditions, the oxidative reaction does not occur Lactiplantibacillus plantarum ? - ? 89 1.1.1.72 additional information glycerol dehydrogenase activity is detected in all Lactobacillus strains studied. This enzyme shows a very low oxidative activity with glycerol and NADP+ and, most likely, under physiological conditions, the oxidative reaction does not occur Lactobacillus delbrueckii ? - ? 89 1.1.1.72 additional information glycerol dehydrogenase activity is detected in all Lactobacillus strains. This enzyme shows a very low oxidative activity with glycerol and NADP+ and, most likely, under physiological conditions, the oxidative reaction does not occur Lactobacillus acidophilus ? - ? 89 1.1.1.72 additional information glycerol dehydrogenase activity is detected in all Lactobacillus strains studied but only for the reduction of glyceraldehyde with NADPH. This enzyme shows a very low oxidative activity with glycerol and NADP+ and, most likely, under physiological conditions, the oxidative reaction does not occur Lactiplantibacillus plantarum ATCC 8014 ? - ? 89 1.1.1.72 additional information glycerol dehydrogenase activity is detected in all Lactobacillus strains studied. This enzyme shows a very low oxidative activity with glycerol and NADP+ and, most likely, under physiological conditions, the oxidative reaction does not occur Lactobacillus delbrueckii UFV-H2B20 ? - ? 89 1.1.1.72 additional information glycerol dehydrogenase activity is detected in all Lactobacillus strains. This enzyme shows a very low oxidative activity with glycerol and NADP+ and, most likely, under physiological conditions, the oxidative reaction does not occur Lactobacillus acidophilus ATCC 4356 ? - ? 89 1.1.1.72 n-butyraldehyde + NADPH - Rattus norvegicus n-butanol + NADP+ - ? 187586 1.1.1.72 n-butyraldehyde + NADPH - Oryctolagus cuniculus n-butanol + NADP+ - ? 187586 1.1.1.72 n-hexanal + NADPH + H+ - Oryctolagus cuniculus n-hexanol + NADP+ - ? 188607 1.1.1.72 n-pentanal + NADPH + H+ - Rattus norvegicus n-pentanol + NADP+ - ? 188600 1.1.1.72 n-pentanal + NADPH + H+ - Oryctolagus cuniculus n-pentanol + NADP+ - ? 188600 1.1.1.72 nonanal + NADPH + H+ reduction reaction. Specific activity: 15.9 micromol/min/mg Gluconobacter oxydans nonanol + NADP+ - ? 415059 1.1.1.72 octan-3-one + NADPH + H+ reduction reaction. Specific activity: 0.02 micromol/min/mg Gluconobacter oxydans octan-3-ol + NADP+ - ? 415068 1.1.1.72 octanal + NADPH + H+ reduction reaction. Specific activity: 35.5 micromol/min/mg Gluconobacter oxydans octanol + NADP+ - ? 374084 1.1.1.72 pentane-1,2-diol + NADP+ oxidation reaction. Specific activity: 0.39 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 415107 1.1.1.72 pentane-1,5-diol + NADP+ oxidation reaction. Specific activity: 0.59 micromol/min/mg Gluconobacter oxydans ? + NADPH - ? 415108 1.1.1.72 propanal + NADPH + H+ reduction reaction. Specific activity: 1.1 micromol/min/mg Gluconobacter oxydans propanol + NADP+ - ? 187613 1.1.1.72 propionaldehyde + NADPH - Rattus norvegicus propanol + NADP+ - ? 139568 1.1.1.72 propionaldehyde + NADPH - Oryctolagus cuniculus propanol + NADP+ - ? 139568