1.1.1.388 D-glucose 6-phosphate + NAD+ the enzyme is specific for D-glucose 6-phosphate. D-Glucose is not oxidized at significant rates. The catalytic efficiency of the enzyme for NAD+ (263/s*mM) is about 230-fold higher than for NADP+ (1.13/s*mM), indicating NAD+ to be the physiological electron acceptor 421938 1.1.1.388 D-glucose 6-phosphate + NADP+ the enzyme is functionally involved in pentose phosphate formation in vivo 421939