2.7.6.2	ATP + thiamine	-	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	the enzyme is a regulator of thiamine metabolism, phosphate metabolism, mating, and growth	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	the enzyme is important for the formation of the coenzyme thiamine diphosphate	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	the tpk-1 gene functions cell nonautonomously, as the expression of wild-type tpk-1 in one tissue can residue the function of other tissues that express only mutant tpk-1. Thiamine diphosphate can be transported across the cell membrane	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	enzyme is involved in biosynthesis of thiamine diphosphate	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	importance of TPP/thiamine in the alpha-oxidation pathway. Most TPP is tightly bound to peroxisomal proteins, most likely to 2-hydroxyacyl-CoA lyase 1, HACL1, or membranes	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	thiamine pyrophosphokinase is required for thiamine cofactor activation in Arabidopsis	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	ATP + thiamine	no TMP kinase activity is shown by either isozymes TPK1 or TPK2	AMP + thiamine diphosphate	-	?	358310	
2.7.6.2	CTP + thiamine	-	CMP + thiamine diphosphate	-	?	358312	
2.7.6.2	CTP + thiamine	31.4% of the activity with ATP	CMP + thiamine diphosphate	-	?	358312	
2.7.6.2	GTP + thiamine	-	GMP + thiamine diphosphate	-	?	358313	
2.7.6.2	GTP + thiamine	18.3% of the activity with ATP	GMP + thiamine diphosphate	-	?	358313	
2.7.6.2	GTP + thiamine	GTP is the preferred nucleotide	GMP + thiamine diphosphate	-	?	358313	
2.7.6.2	additional information	three common intronic variants in the maternal and fetal thiamine pyrophosphokinase gene (TPK1) are associated with birth weight, overview	?	-	?	89	
2.7.6.2	additional information	the YcfN protein acts as a nonspecific adenosylcobinamide kinase enzyme, which is not associated with adenosylcobalamine biosynthesis, but it allows a CobU-deficient strain of serovar Typhimurium to synthesize enough adenosylcobalamine from cobinamide so that the cell can grow. YcfN is required for the phosphorylation of thiamine in the thiamine salvaging pathway of Escherichia coli	?	-	?	89	
2.7.6.2	additional information	thiamine binding site structure, overview	?	-	?	89	
2.7.6.2	oxythiamine + ATP	-	oxythiamine diphosphate + AMP	-	?	389463	
2.7.6.2	pyrithiamine + ATP	its specific activity is 30% lower in comparison to its natural substrate thiamine	pyrithiamine diphosphate + AMP	-	?	389618	
2.7.6.2	pyrithiamine + ATP	inhibits the substrate thiamine	pyrithiamine diphosphate + AMP	-	?	389618	
2.7.6.2	thiamin + ATP	-	thiamindiphosphate + AMP	-	?	386713	
2.7.6.2	thiamine + ATP	-	thiamine diphosphate + AMP	-	?	386714	
2.7.6.2	thiamine + ATP	TPP plays a critical role in the carbohydrate and energy metabolism. It functions as a prosthetic group for the mitochondrial enzyme complexes like pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase and branched chain alpha-keto acid dehydrogenase. In addition, TPP is involved in the cytosolic pentose pathway functioning as coenzyme for transketolase.	thiamine diphosphate + AMP	-	?	386714	
2.7.6.2	UTP + thiamine	-	UMP + thiamine diphosphate	-	?	358311	
2.7.6.2	UTP + thiamine	207% of the activity with ATP	UMP + thiamine diphosphate	-	?	358311