2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	-	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	FAS-A mainly synthesizes the C18 fatty acids oleate and stearate with only traces of palmitate, the major product of FAS-B is pamitate	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	-	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	synthesis of saturated and unsaturated fatty acids, FAS-B cannot synthesize oleic acid	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	S-acetylpantetheine and S-malonylpantetheine and saturated acetyl-CoA derivatives can replace acetyl-CoA and malonyl-CoA	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	palmitoyl-CoA and steraoyl-CoA are main products, myristoyl-CoA is produced in small amounts	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	-	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	-	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	stable multifunctional enzyme complex: carries acetyl-CoA and malonyl-CoA transacylase, beta-ketoacyl reductase, beta-hydroxyacyl dehydrase activities on beta-subunits and condensing enzyme, i.e. beta-ketoacyl synthetase, enoylacyl reductase activities and acyl-carrier-protein components on alpha-subunits	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	-	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	mutants require acyl-CoA primers of 10 or more carbon atoms, maximal activity with 12-14 carbon atoms	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	-	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	primers instead of acetyl-CoA: propionyl-CoA, butyryl-CoA or hexanoyl-CoA	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	-	?	321418	
2.3.1.86	acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+	intermediates are never released into the medium	palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O	-	?	321418	
2.3.1.86	acetyl-CoA + malonyl-CoA + NADH + NADPH	multifunctional enzyme involved in yeast fat metabolism	?	-	?	370342	
2.3.1.86	decanoyl-CoA + malonyl-CoA + NADPH + H+	-	?	-	?	451968	
2.3.1.86	lauroyl-CoA + malonyl-CoA + NADPH + H+	-	?	-	?	451969	
2.3.1.86	additional information	fatty acid synthetases of vertebrates and yeast are stable enzyme complexes of multifunctional polypeptide chains, the fatty acid synthetases of plants and E. coli consist of non-associated individual enzymes	?	-	?	89	
2.3.1.86	additional information	narrow substrate specificity for both the acyl donor and the acyl carrier protein acceptor. Exclusive transfer of malonyl-CoA moieties to the mitochondrial holoacyl carrier protein	?	-	?	89	
2.3.1.86	myristoyl-CoA + malonyl-CoA + NADPH + H+	-	?	-	?	451970	
2.3.1.86	octanoyl-CoA + malonyl-CoA + NADPH + H+	-	?	-	?	451971