1.1.1.145 3beta-hydroxy-DELTA5-steroid dehydrogenase Leydig cell - 668423, 698503, 699111, 740997 1.1.1.146 11beta-hydroxysteroid dehydrogenase Leydig cell - 655347, 670252, 699841, 726493, 741248 1.1.1.188 prostaglandin-F synthase Leydig cell co-localization of cyclooxygenase-1, prostaglandin F receptor and prostaglandin F synthase 687013 1.1.1.239 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) Leydig cell pre- and peri-pubertal changes promote expression of the enzyme in Leydig cells 713574 1.1.1.300 NADP-retinol dehydrogenase Leydig cell - 761195 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase Leydig cell - 686929, 761195 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase Leydig cell 3beta- and 17beta-hydroxysteroid dehydrogenase are not altered in metyrapone-treated cells 690081 1.1.1.62 17beta-estradiol 17-dehydrogenase Leydig cell 3beta- and 17beta-hydroxysteroid dehydrogenase are not altered in metyrapone-treated cells 690081 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+) Leydig cell - 699111, 726493 1.1.1.64 testosterone 17beta-dehydrogenase (NADP+) Leydig cell 17beta-HSD type 3 (HSD17B3) is expressed almost exclusively in testicular Leydig cells 761760 1.1.1.B40 11beta-hydroxysteroid dehydrogenase (NAD+) Leydig cell of neonatal pig. High expression of 11beta-hydroxysteroid dehydrogenase type 2 mRNA, resulting in oxidation from cortisol to cortison, with no detection of the reduction reaction. Activity of type 2 enzyme is higher than the oxidation activity of the type 1 enzyme 693882 1.13.11.71 carotenoid-9',10'-cleaving dioxygenase Leydig cell - 720152 1.14.14.154 sterol 14alpha-demethylase Leydig cell - 671727 1.14.14.17 squalene monooxygenase Leydig cell tumor cell defective in cytochrome P450 17alpha hydroxylase/17,20 lyase activity 659953 1.14.14.19 steroid 17alpha-monooxygenase Leydig cell - 715984 1.14.14.24 vitamin D 25-hydroxylase Leydig cell - 736019 1.14.14.32 17alpha-hydroxyprogesterone deacetylase Leydig cell - 706819 1.14.14.32 17alpha-hydroxyprogesterone deacetylase Leydig cell intensely present during the breeding season and weakly present during the non-breeding season 705389 1.14.15.4 steroid 11beta-monooxygenase Leydig cell - 655347 1.14.15.6 cholesterol monooxygenase (side-chain-cleaving) Leydig cell - 712924, 743937 1.2.3.1 aldehyde oxidase Leydig cell ABCA1 and AOX1 are coexpressed 692569 1.3.1.21 7-dehydrocholesterol reductase Leydig cell progenitor cells, immature cells, and adult cells, differentially expressed transcripts and enzyme expression levels during development and differentiation, overview 656789 1.4.3.1 D-aspartate oxidase Leydig cell - 711719 1.7.2.1 nitrite reductase (NO-forming) Leydig cell MLTC-1 677146 1.8.1.9 thioredoxin-disulfide reductase Leydig cell TXNRD1_v3 is predominantly expressed in the Leydig cells 687762 2.3.1.176 propanoyl-CoA C-acyltransferase Leydig cell - 758130 2.3.1.37 5-aminolevulinate synthase Leydig cell high expression of isoform ALAS1 703855 2.7.1.154 phosphatidylinositol-4-phosphate 3-kinase Leydig cell strong expression of PI3K-C2alpha and moderate expression of PI3K-C2beta 645046 2.7.11.22 cyclin-dependent kinase Leydig cell - 707637 2.7.12.2 mitogen-activated protein kinase kinase Leydig cell - 678560 2.8.2.2 alcohol sulfotransferase Leydig cell - 761704 3.1.1.13 sterol esterase Leydig cell temperature-stabile enzyme enriched 133846 3.1.1.79 hormone-sensitive lipase Leydig cell - -, 730033 3.1.2.2 palmitoyl-CoA hydrolase Leydig cell - 666097 3.1.4.35 3',5'-cyclic-GMP phosphodiesterase Leydig cell phosphodiesterase 5 668864 3.1.6.2 steryl-sulfatase Leydig cell all cells with positive StS expression,exception: 65.1% StS expression in 50-day-old animal's Leydig cells 695080 3.2.1.114 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase Leydig cell in the Golgi apparatus 646640 3.4.11.6 aminopeptidase B Leydig cell - 665109, 666799 3.4.16.5 carboxypeptidase C Leydig cell of testis 665905 3.4.17.23 angiotensin-converting enzyme 2 Leydig cell - 763160 3.4.17.23 angiotensin-converting enzyme 2 Leydig cell ACE2 may participate in the control of the testicular function 668418 3.4.21.34 plasma kallikrein Leydig cell synthesis of prekallikrein 683208 3.4.21.35 tissue kallikrein Leydig cell - 665230, 671024 3.4.21.B42 hippostasin Leydig cell expression revealed by immunohistochemistry 667873 3.4.22.62 caspase-9 Leydig cell - 697784 3.4.23.5 cathepsin D Leydig cell - 731091 3.6.4.13 RNA helicase Leydig cell - 691843 3.6.4.13 RNA helicase Leydig cell the 1 kb fragment (5' to the ATG codon) of GRTH gene contains sequences for androgen regulation of its expression in Leydig cells 712550 4.1.1.15 glutamate decarboxylase Leydig cell - 701446 4.1.1.29 sulfinoalanine decarboxylase Leydig cell - 701655 4.1.1.49 phosphoenolpyruvate carboxykinase (ATP) Leydig cell - 727933 4.3.2.9 gamma-glutamylcyclotransferase Leydig cell weak expression 720332 4.4.1.16 selenocysteine lyase Leydig cell - 730241 4.6.1.2 guanylate cyclase Leydig cell - 679514, 679516 6.2.1.3 long-chain-fatty-acid-CoA ligase Leydig cell - 653671, 661822, 671606, 675688