1.10.5.1 A-549 cell - 763861 1.10.5.1 bile no significant difference in expression in normal and malignant biliary tissue. Activity of NQO2 is significatly lower than in hepatocellular tissue 659967 1.10.5.1 brain - 659111 1.10.5.1 brain minimal expression 657888, 658430 1.10.5.1 brain cortex - 712829 1.10.5.1 embryonic hippocampal cell line - 712829 1.10.5.1 erythrocyte - 659111 1.10.5.1 erythrocyte modest level 657888 1.10.5.1 HCT-116 cell - 711408, 711470 1.10.5.1 heart - 657888, 658430, 659111 1.10.5.1 Hep-G2 cell - 725669, 763913 1.10.5.1 hepatocyte primary hepatocyte 763805 1.10.5.1 hippocampus - 712829 1.10.5.1 K-562 cell - 725669 1.10.5.1 kidney - 657888, 658430, 659111, 659146, 660397 1.10.5.1 liver - 657888, 658430, 658817, 659111, 660397, 673791, 742815, 763913 1.10.5.1 liver hepatic NQO2 concentrations ranges from 2 to 31 microM 764465 1.10.5.1 liver high expression level 657888 1.10.5.1 liver in normal hepatocellular tissue, the two NQO isoforms are differentially regulated with a higher expression of NQO2 than NQO1. In malignant hepatocellular tissue NQO1 is up-regulated and NQO2 is down-regulated 659967 1.10.5.1 lung - 658430 1.10.5.1 additional information no activity in blood plasma 659111 1.10.5.1 additional information no activity in placenta 658430 1.10.5.1 additional information no expression in placenta 657888 1.10.5.1 additional information no expression in skeletal muscle 657888 1.10.5.1 additional information QR2 is overexpressed in neurodegenerative diseases 725158 1.10.5.1 NCI-H1299 cell - 763861 1.10.5.1 NCI-H1975 cell - 763861 1.10.5.1 NCI-H358 cell - 763861 1.10.5.1 NCI-H460 cell - 763861 1.10.5.1 ovary the high NQO2 activity of intraperitoneal ovarian metastases relative to other tissues indicates a potential for tretazicar therapy in the treatment of this disease 686136 1.10.5.1 pancreas minimal expression 657888, 658430 1.10.5.1 prostate gland ventral lobe - 659111 1.10.5.1 seminal vesicle - 659111 1.10.5.1 SH-SY5Y cell - 764767 1.10.5.1 skeletal muscle - 659111 1.10.5.1 skeletal muscle high expression level 657888 1.10.5.1 skeletal muscle highest expression 658430 1.10.5.1 SKOV-3 cell high expression level of NQO2 764623 1.10.5.1 testis - 658817 1.10.5.1 TOV-112D cell low expression level of NQO2 764623 1.10.5.1 vascular smooth muscle cell suppression of vascular smooth muscle cell proliferation mediated by resveratrol correlates with vascular smooth muscle cell downregulation 697413