2.7.4.16	drug target	the enzyme represents a potential drug target for the development of an augmented repertoire of antibiotics against Pseudomonas aeruginosa	761512	
2.7.4.16	metabolism	biosynthesis pathways of thiamine, thiamine phosphate, and thiamine diphosphate, overview	-, 738905	
2.7.4.16	additional information	residue Ser196 plays a pivotal role in the catalytic process	-, 738905	
2.7.4.16	physiological function	in this archaeon, the phosphorylation of thiamine phosphate is the only way to synthesize thiamine diphosphate, it cannot use exogenous thiamine and direct diphosphorylation for the salvage synthesis of thiamine diphosphate	-, 738905