1.3.1.86 malfunction loss of ccr leads to lower levels of the monensin precursor methymalonyl-CoA, relative to coenzyme A 656737 1.3.1.86 malfunction the ability of the ccr deletion mutant of Streptomyces collinus to grow on acetate is dramatically reduced 712270 1.3.1.86 metabolism butyryl-CoA dehydrogenase from C. difficile belongs to the subfamily of bifurcating enzymes capable of coupling the exergonic reduction of crotonyl-CoA by NAD Hwith the endergonic reduction of ferredoxin by NADH -, 725287 1.3.1.86 metabolism the genes necessary for butyrate formation from the genome of Clostridium difficile are expressed in Escherichia coli. The individual genes are assembled in a single plasmid vector into an artificial operon , which allows functional coexpression of the required genes and confers butyrate-forming capability to the host -, 725287 1.3.1.86 physiological function CCR and the butyryl-CoA pathway provide the majority of methylmalonyl-CoA and ethylmalonyl-CoA for monensin A biosynthesis 712641 1.3.1.86 physiological function CCR plays a significant role in providing methylmalonyl-CoA for monensin biosynthesis in oil-based 10-day fermentations of Streptomyces cinnamonensis 656737 1.3.1.86 physiological function CCR provides butyryl-CoA precursor for monensin A biosynthesis 712939 1.3.1.86 physiological function in streptomycetes, Ccr catalyzes the last step in the reductive biosynthesis of butyryl-CoA from two molecules of acetyl-CoA 713435 1.3.1.86 physiological function the ccr gene is involved in a novel butytryl-CoA pathway for the growth of Streptomyces collinus when acetate is its sole carbon source 712270 1.3.1.86 physiological function the enzyme (EgTER1) is involved in the greening process. It is dispensable for wax ester production under anaerobic conditions 763623