1.14.18.11 malfunction when silencing the enzyme, an important accumulation of 4alpha-methyl-DELTA7-sterols is found, with no change in the levels of 4,4-dimethylsterols 752272 1.14.18.11 metabolism enzyme expression in a yeast erg25 ergosterol auxotroph, lacking sterol-4alpha-methyl oxidase activity, restores growth and endogenous ergosterol synthesis 750534 1.14.18.11 metabolism the enzyme is involved in the removal of the second C4-methyl group of phytosterol precursors 752272