4.1.99.19	physiological function	involved in the biosynthesis of the thiazole moiety of thiamine	
4.1.99.19	physiological function	the enzyme complex ThiGH is involved in the rate-limiting step of thiamine biosynthesis	
4.1.99.19	physiological function	the enzyme is essential for thiazole biosynthesis in Escherichia coli	
4.1.99.19	physiological function	the enzyme is required for the synthesis of the 4-methyl-5-hydroxyethyl-thiazole monophosphate moiety of thiamine diphosphate