2.2.1.7	malfunction	isoform DXS2 downregulation of leads to a significant decrease of tanshinone accumulation in transgenic roots	757643	
2.2.1.7	malfunction	knockout mutations with lethal albino plants	699265	
2.2.1.7	malfunction	The wls-2297 mutant enzyme's severe deficiency in chlorophylls and carotenoids promotes an albino phenotype. Additionally, growth of enzyme mutant seedlings is arrested without developing vegetative organs, which results in premature lethality	758411	
2.2.1.7	metabolism	enzyme overexpression significantly enhances tanshinone accumulation in transgenic roots	757643	
2.2.1.7	metabolism	enzyme overexpression significantly enhances tanshinone accumulation in transgenic roots. Isoform DXS2 is an important rate-limiting gene in the methylerythritol 4-phosphate pathway involved in tanshinone biosynthesis	757643	
2.2.1.7	metabolism	rate-limiting enzyme in the 2-C-methyl-D-erythritol 4-phosphate pathway, which is responsible for the production of precursors of all isoprenoids	757263	
2.2.1.7	metabolism	the enzyme functions in pine oleoresin biosynthesis	756215	
2.2.1.7	metabolism	the enzyme plays an essential role in the control of taxol biosynthesis	756492	
2.2.1.7	metabolism	the enzyme primarily exerts the control flux of the methylerythritol 4-phosphate pathway	736693	
2.2.1.7	physiological function	first enzyme in 2C-methyl-D-erythritol 4-phosphate pathway, rate-limiting of isoprenoid biosynthesis	705372	
2.2.1.7	physiological function	first enzyme in plastididal pathway of terpene biosynthesis	706809	
2.2.1.7	physiological function	first enzyme of the methyl-D-erythritol 4-phsophate pathway in plants, influence on isoprenoid synthesis	699265	
2.2.1.7	physiological function	first enzyme of the methyl-D-erythritol 4-phsophate pathway in plants, influence on isoprenoid synthsese	699265	
2.2.1.7	physiological function	involved in the 2-C-methyl-D-erythritol 4-phosphate pathway	701348	
2.2.1.7	physiological function	part of meyalonate-independent 2-C-methyl-D-erythritol 4-phosphate pathway, production of essential isoprenoid precursors	706051	
2.2.1.7	physiological function	required for the synthesis of the non-isoprenoid vitamins thiamine and pyridoxal	699265	
2.2.1.7	physiological function	the enzyme is essentially required for the development and survival of tomato plants	758411