4.99.1.9	physiological function	coproporpyhrin III is the substrate of coproporphyrin ferrochelatases (CpfCs). These enzymes catalyse the insertion of ferrous iron into the porphyrin ring. This is the penultimate step within the coproporphyrin-dependent heme biosynthesis pathway. In the CPD pathway, CpfC produces iron coproporphyrin III (coproheme), which is the substrate for coproheme decarboxylase (ChdC)	771075	
4.99.1.9	physiological function	hemH mutants accumulate all three tetrapyrroles: uroporphyrin, coproporphyrin, and protoporphyrin. Porphyrin accumulation does not occur in these mutants (in a hemA4 background) in the absence of 5-aminolevulinic acid	738498