1.1.1.105 down expression of the native RDHE2 is downregulated in the presence of elevated levels of all-trans-retinoic acid 738036 1.1.1.105 down insulin decreases Rdh10 and Rdh16 mRNA in HepG2 cells incubated in serum-free medium by inhibiting transcription and destabilizing mRNA 738670 1.1.1.105 down oral gavage with glucose or injection with insulin decreases Rdh1 mRNA 50% or greater in mouse liver 738670 1.1.1.105 up removing serum from the medium of the human hepatoma cell line HepG2 increases isoforms Rdh10 and Rdh16 mRNA expression 2-3-fold by 4 h, by increasing transcription and stabilizing mRNA 738670