1.14.11.68 down GSK-J4 reduces both the mRNA and protein levels of mPR3 significantly compared to controls 1.14.11.68 up Jmjd3 expression is upregulated at the outset of neural commitment 1.14.11.68 up JMJD3 is upregulated in prostate cancer, and its expression is higher in metastatic prostate cancer 1.14.11.68 up lipopolysaccharide (LPS) induces JMJD3 expression in vitro. Neutrophil JMJD3 expression is increased in patients with sepsis compared to controls 1.14.11.68 up presence of nickel chloride upregulates the expression of H3K27me3 demethylase Jmjd3 in kidney cancer cells, which is accompanied by the reduction in the protein level of H3K27me3