2.3.1.12 755757 Pyrene degradation by Chlorella sp. MM3 in liquid medium and soil slurry Possible role of dihydrolipoamide acetyltransferase in pyrene biodegradation Algal Res. 23 223-232 2017 Chlorella sp. MM3 - 2.3.1.12 486203 A kinetic study of dihydrolipoyl transacetylase from bovine kidney J. Biol. Chem. 250 1921-1925 1975 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1089667&form=6&db=m 2.3.1.12 486204 A new dihydrolipoamide transacetylase in Escherichia coli K12 Biochim. Biophys. Acta 321 143-148 1973 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4584392&form=6&db=m 2.3.1.12 674601 A new level of architectural complexity in the human pyruvate dehydrogenase complex J. Biol. Chem. 281 19772-19780 2006 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16679318&form=6&db=m 2.3.1.12 486208 alpha-Keto acid dehydrogenase complexes. IX. Effects of iodination of the tyrosyl residues on the properties of the dihydrolipoyl transacetylase of Escherichia coli J. Biol. Chem. 243 639-643 1968 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4866524&form=6&db=m 2.3.1.12 486210 alpha-Keto acid dehydrogenase complexes. VI. Dissociation and reconstitution of the dihydrolipoyl transacetylase of Escherichia coli J. Biol. Chem. 242 889-897 1967 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5335914&form=6&db=m 2.3.1.12 486209 alpha-Keto acid dehydrogenase complexes. VII. Isolation and partial characterization of the polypeptide chains in the dihydrolipoyl transacetylase of Escherichia coli J. Biol. Chem. 242 898-901 1967 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=5335915&form=6&db=m 2.3.1.12 486207 alpha-Keto acid dehydrogenase complexes. XII. Effects of acetylation on the activity and structure of the dihydrolipoyl transacetylase of Escherichia coli J. Biol. Chem. 244 6074-6079 1969 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4900507&form=6&db=m 2.3.1.12 94893 alpha-Keto acid dehydrogenase complexes. XV. Purification and properties of the component enzymes of the pyruvate dehydrogenase complexes from bovine kidney and heart Arch. Biochem. Biophys. 148 327-342 1972 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4401694&form=6&db=m 2.3.1.12 486178 Amino acid sequence analysis of the lipoyl and peripheral subunit-binding domains in the lipoate acetyltransferase component of the pyruvate dehydrogenase complex from Bacillus stearothermophilus Biochem. J. 252 79-86 1988 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3421911&form=6&db=m 2.3.1.12 486240 Assembly and full functionality of recombinantly expressed dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex J. Biol. Chem. 272 6361-6369 1997 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9045657&form=6&db=m 2.3.1.12 486217 Binding and dissociation of the pyruvate dehydrogenase complex of Azotobacter vinelandii on thiol--Sepharose FEBS Lett. 143 261-264 1982 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7117532&form=6&db=m 2.3.1.12 686772 Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex FEBS Lett. 582 468-472 2008 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18206651&form=6&db=m 2.3.1.12 486195 Bovine kidney pyruvate dehydrogenase complex. Limited proteolysis and molecular structure of the lipoate acetyltransferase component Eur. J. Biochem. 112 589-599 1980 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6780350&form=6&db=m 2.3.1.12 663011 Central organization of mammalian pyruvate dehydrogenase (PD) complex and lipoyl domain-mediated activated function and control of PD kinases and phosphatase 1 Oxid. Stress Dis. 11 363-386 2004 Homo sapiens - 2.3.1.12 663011 Central organization of mammalian pyruvate dehydrogenase (PD) complex and lipoyl domain-mediated activated function and control of PD kinases and phosphatase 1 Oxid. Stress Dis. 11 363-386 2004 Rattus norvegicus - 2.3.1.12 486232 Characterization of the dihydrolipoamide acetyltransferase of the mitochondrial pyruvate dehydrogenase complex from potato and comparisons with similar enzymes in diverse plant species Eur. J. Biochem. 264 973-981 1999 Solanum tuberosum http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10491147&form=6&db=m 2.3.1.12 486227 Cloning and characterization of a dihydrolipoamide acetyltransferase (E2) subunit of the pyruvate dehydrogenase complex from Arabidopsis thaliana J. Biol. Chem. 270 5412-5417 1995 Arabidopsis thaliana http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7890655&form=6&db=m 2.3.1.12 486233 Cloning and characterization of the dihydrolipoamide S-acetyltransferase subunit of the plastid pyruvate dehydrogenase complex (E2) from Arabidopsis Plant Physiol. 120 443-452 1999 Arabidopsis thaliana http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10364395&form=6&db=m 2.3.1.12 486169 Cloning and nucleotide sequence of the gene for dihydrolipoamide acetyltransferase from Saccharomyces cerevisiae Proc. Natl. Acad. Sci. USA 85 7546-7550 1988 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3050999&form=6&db=m 2.3.1.12 393963 Cloning and sequence analysis of the genes encoding the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus Eur. J. Biochem. 194 95-102 1990 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2253629&form=6&db=m 2.3.1.12 348982 Cloning and sequence analysis of the pyruvate and 2-oxoglutarate dehydrogenase complex genes of Escherichia coli Biochem. Soc. Trans. 12 220-223 1984 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6373436&form=6&db=m 2.3.1.12 486224 Cloning, sequencing, characterization and implications for vaccine design of the novel dihydrolipoyl acetyltransferase of Neisseria meningitidis J. Med. Microbiol. 45 419-432 1996 Neisseria meningitidis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8958245&form=6&db=m 2.3.1.12 486199 Crystallization of a dihydrolipoyl transacetylase - dihydrolipoyl dehydrogenase subcomplex and its implications regarding the subunit structure of the pyruvate dehydrogenase complex from Escherichia coli Biochem. Biophys. Res. Commun. 90 431-438 1979 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=389239&form=6&db=m 2.3.1.12 486228 Crystallographic and enzymatic investigations on the role of Ser558, His610, and Asn614 in the catalytic mechanism of Azotobacter vinelandii dihydrolipoamide acetyltransferase (E2p) Biochemistry 34 4287-4298 1995 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7703242&form=6&db=m 2.3.1.12 675426 Distinct modes of recognition of the lipoyl domain as substrate by the E1 and E3 components of the pyruvate dehydrogenase multienzyme complex J. Mol. Biol. 366 132-139 2006 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17157320&form=6&db=m 2.3.1.12 486176 Domain structures of the dihydrolipoyl transacetylase and the protein X components of mammalian pyruvate dehydrogenase complex. Selective cleavage by protease Arg C J. Biol. Chem. 264 1245-1251 1989 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2642901&form=6&db=m 2.3.1.12 642164 Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 Eur. J. Biochem. 270 1050-1056 2003 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12631265&form=6&db=m 2.3.1.12 642164 Essential roles of lipoyl domains in the activated function and control of pyruvate dehydrogenase kinases and phosphatase isoform 1 Eur. J. Biochem. 270 1050-1056 2003 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12631265&form=6&db=m 2.3.1.12 663289 Expression and purification of the dihydrolipoamide acetyltransferase and dihydrolipoamide dehydrogenase subunits of the Escherichia coli pyruvate dehydrogenase multienzyme complex: a mass spectrometric assay for reductive acetylation of dihydrolipoamide acetyltransferase Protein Expr. Purif. 28 140-150 2003 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12651118&form=6&db=m 2.3.1.12 486167 Expression in Escherichia coli of a sub-gene encoding the lipoyl domain of the pyruvate dehydrogenase complex of Bacillus stearothermophilus [published erratum appears in FEBS Lett 1990 Jul 30;268(1):306] FEBS Lett. 264 206-210 1990 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2192914&form=6&db=m 2.3.1.12 662151 Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase J. Biol. Chem. 278 33681-33693 2003 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12816949&form=6&db=m 2.3.1.12 486181 Genetic reconstruction and functional analysis of the repeating lipoyl domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli J. Mol. Biol. 185 743-754 1985 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3903169&form=6&db=m 2.3.1.12 486229 Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex, Identification of important amino acid residues Biochem. J. 334 703-711 1998 Homo sapiens - 2.3.1.12 348932 Hybrid pyruvate dehydrogenase complexes reconstituted from components of the complexes from Escherichia coli and Azotobacter vinelandii Eur. J. Biochem. 152 35-41 1985 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3899642&form=6&db=m 2.3.1.12 348932 Hybrid pyruvate dehydrogenase complexes reconstituted from components of the complexes from Escherichia coli and Azotobacter vinelandii Eur. J. Biochem. 152 35-41 1985 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3899642&form=6&db=m 2.3.1.12 735426 Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS Anal. Bioanal. Chem. 408 1557-1564 2016 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=26753982&form=6&db=m 2.3.1.12 725521 Insight to the interaction of the dihydrolipoamide acetyltransferase (E2) core with the peripheral components in the Escherichia coli pyruvate dehydrogenase complex via multifaceted structural approaches J. Biol. Chem. 288 15402-15417 2013 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=23580650&form=6&db=m 2.3.1.12 673523 Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Use of a truncated protein domain in NMR spectroscopy FEBS J. 272 259-268 2005 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=15634348&form=6&db=m 2.3.1.12 661632 Interactions of the peripheral subunit-binding domain of the dihydrolipoyl acetyltransferase component in the assembly of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus Eur. J. Biochem. 270 4488-4496 2003 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14622277&form=6&db=m 2.3.1.12 486216 Isolation and characterization of a membrane-bound pyruvate dehydrogenase complex from the phototropic bacterium Rhodopseudomonas capsulata Z. Naturforsch. C 32c 351-361 1977 Rhodospirillum rubrum - 2.3.1.12 486166 Isolation and characterization of lipoylated and unlipoylated domains of the E2p subunit of the pyruvate dehydrogenase complex of Escherichia coli Biochem. J. 271 139-145 1990 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2121129&form=6&db=m 2.3.1.12 486179 Isolation of a cDNA clone for the dihydrolipoamide acetyltransferase component of the human liver pyruvate dehydrogenase complex Biochem. Biophys. Res. Commun. 145 903-907 1987 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3036145&form=6&db=m 2.3.1.12 674544 Ligand-induced effects on pyruvate dehydrogenase kinase isoform 2 J. Biol. Chem. 281 12568-12579 2006 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16517984&form=6&db=m 2.3.1.12 486184 Limited proteolysis of the pyruvate dehydrogenase multienzyme complex of Bacillus subtilis Biochem. J. 225 249-253 1985 Bacillus subtilis http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3919704&form=6&db=m 2.3.1.12 486197 Mammalian lipoate acetyltransferase: molecular weight determination by gel filtration in the presence of guanidinium chloride FEBS Lett. 112 48-50 1980 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6768590&form=6&db=m 2.3.1.12 348927 Mammalian pyruvate dehydrogenase complex binds tightly to the mitochondrial inner membrane Biochem. Soc. Trans. 14 893 1986 Bos taurus - 2.3.1.12 720722 Mapping the lipoylation site of Arabidopsis thaliana plastidial dihydrolipoamide S-acetyltransferase using mass spectrometry and site-directed mutagenesis Plant Physiol. Biochem. 49 1355-1361 2011 Arabidopsis thaliana http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=21798751&form=6&db=m 2.3.1.12 486180 Molecular cloning of cDNA for rat liver lipoate acetyltransferase. A component of pyruvate dehydrogenase complex Biochem. Biophys. Res. Commun. 142 953-957 1987 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2950858&form=6&db=m 2.3.1.12 348961 Molecular cloning of the pyruvate dehydrogenase complex genes of Escherichia coli J. Gen. Microbiol. 121 277-292 1980 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6455499&form=6&db=m 2.3.1.12 486239 Molecular cloning, and characterization and expression of dihydrolipoamide acetyltransferase component of murine pyruvate dehydrogenase complex in bile duct cancer cells J. Gastroenterol. 37 449-454 2002 Mus musculus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=12108679&form=6&db=m 2.3.1.12 674743 Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy J. Biol. Chem. 281 4364-4370 2006 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=16308322&form=6&db=m 2.3.1.12 348967 Molecular weight and symmetry of the pyruvate dehydrogenase multienzyme complex of Escherichia coli J. Mol. Biol. 129 603-617 1979 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=383998&form=6&db=m 2.3.1.12 736459 Novel binding motif and new flexibility revealed by structural analyses of a pyruvate dehydrogenase-dihydrolipoyl acetyltransferase subcomplex from the Escherichia coli pyruvate dehydrogenase multienzyme complex J. Biol. Chem. 289 30161-30176 2014 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=25210042&form=6&db=m 2.3.1.12 486230 Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase Structure 4 277-286 1996 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8805537&form=6&db=m 2.3.1.12 486237 Purification and cellular localization of wild type and mutated dihydrolipoyltransacetylases from Azotobacter vinelandii and Escherichia coli expressed in E. coli Biochim. Biophys. Acta 1120 87-96 1992 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1554745&form=6&db=m 2.3.1.12 486237 Purification and cellular localization of wild type and mutated dihydrolipoyltransacetylases from Azotobacter vinelandii and Escherichia coli expressed in E. coli Biochim. Biophys. Acta 1120 87-96 1992 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1554745&form=6&db=m 2.3.1.12 486168 Purification and characterization of acetoin:2,6-dichlorophenolindophenol oxidoreductase, dihydrolipoamide dehydrogenase, and dihydrolipoamide acetyltransferase of the Pelobacter carbinolicus acetoin dehydrogenase enzyme system J. Bacteriol. 173 757-767 1991 Syntrophotalea carbinolica http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1898934&form=6&db=m 2.3.1.12 348941 Purification and immunochemical studies of pyruvate dehydrogenase complex from rat heart, and cell-free synthesis of lipoamide dehydrogenase, a component of the complex Biochim. Biophys. Acta 741 86-93 1983 Rattus norvegicus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6412756&form=6&db=m 2.3.1.12 348948 Purification and properties of the pyruvate dehydrogenase complex from Salmonella typhimurium and formation of hybrids with the enzyme complex from Escherichia coli Biochim. Biophys. Acta 705 210-217 1982 Salmonella enterica subsp. enterica serovar Typhimurium http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7052136&form=6&db=m 2.3.1.12 348964 Purification and some properties of the pyruvate dehydrogenase complex of Bacillus subtilis FEMS Microbiol. Lett. 9 227-232 1980 Bacillus subtilis - 2.3.1.12 486202 Purification properties and subunit composition of pig heart lipoate acetyltransferase J. Biochem. 78 187-197 1975 Sus scrofa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1194249&form=6&db=m 2.3.1.12 348965 Purificaton of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus and resolution of its four component polypeptides Biochem. J. 189 161-172 1980 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7458900&form=6&db=m 2.3.1.12 94881 Pyruvate dehydrogenase The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ) 18 77-95 1987 Geobacillus stearothermophilus - 2.3.1.12 94881 Pyruvate dehydrogenase The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ) 18 77-95 1987 Mammalia - 2.3.1.12 348959 Pyruvate dehydrogenase complex from bakers yeast. 2. Molecular structure, dissociation, and implications for the origin of mitochondria Eur. J. Biochem. 119 581-587 1981 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7030741&form=6&db=m 2.3.1.12 348955 Pyruvate dehydrogenase complex from bovine kidney and heart Methods Enzymol. 89 376-386 1982 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7144580&form=6&db=m 2.3.1.12 348951 Pyruvate dehydrogenase complex from broccoli and cauliflower Methods Enzymol. 89 408-414 1982 Brassica oleracea - 2.3.1.12 348951 Pyruvate dehydrogenase complex from broccoli and cauliflower Methods Enzymol. 89 408-414 1982 Brassica oleracea var. botrytis - 2.3.1.12 348949 Pyruvate dehydrogenase complex from Hansenula Methods Enzymol. 89 420-423 1982 Hansenula miso http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7144582&form=6&db=m 2.3.1.12 348954 Pyruvate dehydrogenase complex from Neurospora Methods Enzymol. 89 386-391 1982 Neurospora crassa http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6216392&form=6&db=m 2.3.1.12 348950 Pyruvate dehydrogenase complex from pigeon breast muscle Methods Enzymol. 89 414-420 1982 Columba sp. http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7144581&form=6&db=m 2.3.1.12 486192 Pyruvate dehydrogenase multienzyme complex of Escherichia coli: determination of the Mr of the lipoate acetyltransferase component FEBS Lett. 133 112-114 1981 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7030782&form=6&db=m 2.3.1.12 348946 Reassociation of the pyruvate dehydrogenase complex from Escherichia coli: Kinetic measurements and binding studies by resonance energy transfer Biochemistry 21 1386-1394 1982 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=7041975&form=6&db=m 2.3.1.12 672273 Recognition of the inner lipoyl-bearing domain of dihydrolipoyl transacetylase and of the blood glucose-lowering compound AZD7545 by pyruvate dehydrogenase kinase 2 Biochemistry 46 8592-8602 2007 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17602666&form=6&db=m 2.3.1.12 486201 Reconstitution of the Escherichia coli pyruvate dehydrogenase complex Proc. Natl. Acad. Sci. USA 72 3068-3072 1975 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1103138&form=6&db=m 2.3.1.12 486231 Refolding and reconstitution studies on the transacetylase-protein X (E2/X) subcomplex of the mammalian pyruvate dehydrogenase complex: Evidence for specific binding of the dihydrolipoamide dehydrogenase component to sites on reassembled E2 Biochemistry 36 6819-6826 1997 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9184165&form=6&db=m 2.3.1.12 486186 Repeating functional domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli EMBO J. 3 1315-1319 1984 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6430694&form=6&db=m 2.3.1.12 486174 Separation of protein X from the dihydrolipoyl transacetylase component of the mammalian pyruvate dehydrogenase complex and function of protein X J. Biol. Chem. 264 3655-3657 1989 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2917967&form=6&db=m 2.3.1.12 486235 Sizing of bovine heart and kidney pyruvate dehydrogenase complex and dihydrolipoyl transacetylase core by quasielastic light scattering Biochemistry 32 5629-5637 1993 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=8504083&form=6&db=m 2.3.1.12 702229 Specific ion influences on self-association of pyruvate dehydrogenase kinase isoform 2 (PDHK2), binding of PDHK2 to the L2 lipoyl domain, and effects of the lipoyl group-binding site inhibitor, Nov3r Biochemistry 47 2312-2324 2008 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18220415&form=6&db=m 2.3.1.12 704423 Structural and functional insights into the molecular mechanisms responsible for the regulation of pyruvate dehydrogenase kinase 2 J. Biol. Chem. 283 15789-15798 2008 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18387944&form=6&db=m 2.3.1.12 736448 Structure and function of the catalytic domain of the dihydrolipoyl acetyltransferase component in Escherichia coli pyruvate dehydrogenase complex J. Biol. Chem. 289 15215-15230 2014 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=24742683&form=6&db=m 2.3.1.12 690088 Structures of the human pyruvate dehydrogenase complex cores: a highly conserved catalytic center with flexible N-terminal domains Structure 16 104-114 2008 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=18184588&form=6&db=m 2.3.1.12 704473 Subunit and catalytic component stoichiometries of an in vitro reconstituted human pyruvate dehydrogenase complex J. Biol. Chem. 284 13086-13098 2009 Homo sapiens http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=19240034&form=6&db=m 2.3.1.12 486175 Subunit associations in the mammalian pyruvate dehydrogenase complex. Structure and role of protein X and the pyruvate dehydrogenase component binding domain of the dihydrolipoyl transacetylase component J. Biol. Chem. 264 2221-2227 1989 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2914903&form=6&db=m 2.3.1.12 348938 Subunit binding in the pyruvate dehydrogenase complex from bovine kidney and heart Biochemistry 23 221-226 1984 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6546521&form=6&db=m 2.3.1.12 486196 Subunit structure of dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex from bovine kidney Hoppe-Seyler's Z. Physiol. Chem. 361 1093-1106 1980 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6893315&form=6&db=m 2.3.1.12 486194 Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from bovine heart J. Biol. Chem. 256 514-519 1981 Bos taurus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6778866&form=6&db=m 2.3.1.12 486198 Subunit structure of dihydrolipoyl transacetylase component of pyruvate dehydrogenase complex from Escherichia coli Proc. Natl. Acad. Sci. USA 76 4385-4389 1979 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=388441&form=6&db=m 2.3.1.12 486225 The catalytic domain of dihydrolipoyl acetyltransferase from the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus. Expression, purification and reversible denaturation FEBS Lett. 413 339-343 1997 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=9280309&form=6&db=m 2.3.1.12 486236 The catalytic domain of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli. Expression, purification, properties and preliminary X-ray analysis Eur. J. Biochem. 201 561-568 1991 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1935951&form=6&db=m 2.3.1.12 486236 The catalytic domain of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii and Escherichia coli. Expression, purification, properties and preliminary X-ray analysis Eur. J. Biochem. 201 561-568 1991 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=1935951&form=6&db=m 2.3.1.12 674890 The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension J. Biol. Chem. 282 6161-6171 2007 Saccharomyces cerevisiae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=17200108&form=6&db=m 2.3.1.12 486238 The dihydrolipoamide S-acetyltransferase subunit of the mitochondrial pyruvate dehydrogenase complex from maize contains a single lipoyl domain J. Biol. Chem. 274 21769-21775 1999 Zea mays http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=10419491&form=6&db=m 2.3.1.12 486171 The dihydrolipoyltransacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii. Molecular cloning and sequence analysis Eur. J. Biochem. 174 593-599 1988 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3292237&form=6&db=m 2.3.1.12 486173 The domain structure of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii Eur. J. Biochem. 169 245-252 1987 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3691494&form=6&db=m 2.3.1.12 486170 The gene encoding dihydrolipoyl transacetylase from Azotobacter vinelandii. Expression in Escherichia coli and activation and isolation of the protein Eur. J. Biochem. 181 47-53 1989 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2653824&form=6&db=m 2.3.1.12 348910 The mammalian 2-oxoacid dehydrogenases: a complex family Trends Biochem. Sci. 11 293-296 1986 Bos taurus - 2.3.1.12 348910 The mammalian 2-oxoacid dehydrogenases: a complex family Trends Biochem. Sci. 11 293-296 1986 Mammalia - 2.3.1.12 348910 The mammalian 2-oxoacid dehydrogenases: a complex family Trends Biochem. Sci. 11 293-296 1986 Sus scrofa - 2.3.1.12 661817 The pyruvate dehydrogenase complex of Mycoplasma hyopneumoniae contains a novel lipoyl domain arrangement Gene 319 99-106 2003 Mycoplasma hyopneumoniae http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=14597175&form=6&db=m 2.3.1.12 486172 The quaternary structure of the dihydrolipoyl transacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii. A reconsideration Eur. J. Biochem. 179 287-292 1989 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=2917567&form=6&db=m 2.3.1.12 486185 The size of the pyruvate dehydrogenase complex of Azotobacter vinelandii. Association phenomena Eur. J. Biochem. 140 273-280 1984 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=6714233&form=6&db=m 2.3.1.12 486206 The subunit structure of the Escherichia coli K-12 pyruvate dehydrogenase complex. The dihydrolipoamide transacetylase component Eur. J. Biochem. 20 169-178 1971 Escherichia coli http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=4934679&form=6&db=m 2.3.1.12 486226 Thermally induced changes of lipoate acetyltransferase inner core isolated from the Bacillus stearothermophilus pyruvate dehydrogenase complex Biosci. Biotechnol. Biochem. 65 698-701 2001 Geobacillus stearothermophilus http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=11330694&form=6&db=m 2.3.1.12 486177 Time-resolved fluorescence studies on the dihydrolipoyl transacetylase (E2) component of the pyruvate dehydrogenase complex from Azotobacter vinelandii FEBS Lett. 238 285-288 1988 Azotobacter vinelandii http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?uid=3169263&form=6&db=m